caa a22 4500 469050004 CHVBK 20180323132828.0 cr unu---uuuuu 170328e19921201xx s 000 0 eng 10.1007/BF02974102 doi (NATIONALLICENCE)springer-10.1007/BF02974102 Effects of barbiturates on the rotational relaxation time of 1,6-diphenyl-1,3,5-hexatriene in native and model membranes [Elektronische Daten] [Yong-Za Chung, Yong-Hee Shin, Chang-Hwa Choi, Hyung-Sook Park, Yeong-Sim Koh, Il Yun] Synaptosomal plasma membrane vesicles (SPMV) were isolated from fresh bovine cerebral cortex. The effects of barbiturates on the rotational relaxation time of 1,6-diphenyl-1,3,5-hexatriene (DPH) in intact SPMV and model membranes of total lipids (SPMVTL) and phospholipids (SPMVPL) extracted from SPMV were examined. Barbiturates decreased the rotational relaxation time of DPH in intact SPMV in a dose-dependent manner. In contrast, they did not affect the rotational relaxation time of DPH in SPMVTL and even dose-dependently increased the rotational relaxation time of DPH in SPMVPL. The Pharmaceutical Society of Korea, 1992 Barbiturates nationallicence native and model membranes nationallicence fluidity nationallicence fluorescent probe technique nationallicence Chung Yong-Za Department of Biochemistry, College of Pharmacy, Kyungsung University, 608-736, Pusan, Korea aut Shin Yong-Hee Department of Pharmaceutics, College of Pharmacy, Kyungsung University, 608-736, Pusan, Korea aut Choi Chang-Hwa Department of Neurosurgery, College of Medicine, Pusan National University, 602-739, Pusan, Korea aut Park Hyung-Sook Department of Fundamental Nursing, College of Medicine, Pusan National University, 602-739, Pusan, Korea aut Koh Yeong-Sim Department of Chemistry College of Natural Sciences, Pusan National University, 609-735, Pusan, Korea aut Yun Il Department of Dental Pharmacology and Biophysics, College of Dentistry, Pusan National University, 602-739, Pusan, Korea aut Archives of Pharmacal Research Pharmaceutical Society of Korea 15/4(1992-12-01), 298-303 0253-6269 15:4<298 1992 15 12272 https://doi.org/10.1007/BF02974102 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02974102 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chung Yong-Za Department of Biochemistry, College of Pharmacy, Kyungsung University, 608-736, Pusan, Korea aut NATIONALLICENCE 700 1- Shin Yong-Hee Department of Pharmaceutics, College of Pharmacy, Kyungsung University, 608-736, Pusan, Korea aut NATIONALLICENCE 700 1- Choi Chang-Hwa Department of Neurosurgery, College of Medicine, Pusan National University, 602-739, Pusan, Korea aut NATIONALLICENCE 700 1- Park Hyung-Sook Department of Fundamental Nursing, College of Medicine, Pusan National University, 602-739, Pusan, Korea aut NATIONALLICENCE 700 1- Koh Yeong-Sim Department of Chemistry College of Natural Sciences, Pusan National University, 609-735, Pusan, Korea aut NATIONALLICENCE 700 1- Yun Il Department of Dental Pharmacology and Biophysics, College of Dentistry, Pusan National University, 602-739, Pusan, Korea aut NATIONALLICENCE 773 0- Archives of Pharmacal Research Pharmaceutical Society of Korea 15/4(1992-12-01), 298-303 0253-6269 15:4<298 1992 15 12272 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer