caa a22 4500 469050039 CHVBK 20180323132828.0 cr unu---uuuuu 170328e19921201xx s 000 0 eng 10.1007/BF02974112 doi (NATIONALLICENCE)springer-10.1007/BF02974112 Antitumor activity of Psoralea corylifolia [Elektronische Daten] [Shi Ryu, Sang Choi, Chong Lee, Ok Zee] The activity-oriented fractionation ofPsoralea corylifolia led to an isolation of a (+)-bakuchiol1 as an active principle of its antitumoral propertyin vitro.1 was observed to exhibit a mild cytotoxicity against five kinds of cultured human cancer cell lines,i.e. the A549, SK-OV-3, SK-MEL-2, XF498 and HCT15. The synthesized 2,3-epoxide of (+)-bakuchiol3 showed the similar activity as the (+)-bakuchiol1, whereas the other oxidation derivatives4 and5 including the acetyl-(+)-bakuchiol2 showed a decreased activity. The Pharmaceutical Society of Korea, 1992 Psoralea corylifolia nationallicence Leguminosae nationallicence bakuchiol nationallicence antitumoral nationallicence Ryu Shi Korea Research Institute of Chemical Technology, 305-606, Taejeon, Korea aut Choi Sang Korea Research Institute of Chemical Technology, 305-606, Taejeon, Korea aut Lee Chong Korea Research Institute of Chemical Technology, 305-606, Taejeon, Korea aut Zee Ok Korea Research Institute of Chemical Technology, 305-606, Taejeon, Korea aut Archives of Pharmacal Research Pharmaceutical Society of Korea 15/4(1992-12-01), 356-359 0253-6269 15:4<356 1992 15 12272 https://doi.org/10.1007/BF02974112 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02974112 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ryu Shi Korea Research Institute of Chemical Technology, 305-606, Taejeon, Korea aut NATIONALLICENCE 700 1- Choi Sang Korea Research Institute of Chemical Technology, 305-606, Taejeon, Korea aut NATIONALLICENCE 700 1- Lee Chong Korea Research Institute of Chemical Technology, 305-606, Taejeon, Korea aut NATIONALLICENCE 700 1- Zee Ok Korea Research Institute of Chemical Technology, 305-606, Taejeon, Korea aut NATIONALLICENCE 773 0- Archives of Pharmacal Research Pharmaceutical Society of Korea 15/4(1992-12-01), 356-359 0253-6269 15:4<356 1992 15 12272 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer