caa a22 4500 469050152 CHVBK 20180323132828.0 cr unu---uuuuu 170328e19920601xx s 000 0 eng 10.1007/BF02974086 doi (NATIONALLICENCE)springer-10.1007/BF02974086 Effect of urea derivatives on the critical micelle concentration of polyoxyethylated nonionic surfactant [Elektronische Daten] [Suk Han, Min Kim, Yong Park, Jeong Lee, Jin Back] The critical micelle concentrations (CMCs) of aqueous solutions of a nonionic surfactant, polyoxyl 23 lauryl ether in the presence of various concentration of urea and its derivatives were measured. The CMC of the surfactant increased in proportion to the concentration of the additives, and the CMC-raising activities increased with more and longer alkyl groups substituted in urea. The CMC shift values were successfully correlated with the cloud point shift values and the protein-denaturing activities of the additives, respectively. These results suggest that the micelle formation, clouding of the surfactant and the protein denaturation are a closely related phenomenon, and a common mechanism is operating which might be the hydrophobic interaction. The Pharmaceutical Society of Korea, 1992 Critical micelle concentration nationallicence urea nationallicence nonionic surfactant nationallicence Han Suk College of Pharmacy, Pusan National University, 609-735, Pusan, Korea aut Kim Min College of Pharmacy, Pusan National University, 609-735, Pusan, Korea aut Park Yong College of Pharmacy, Pusan National University, 609-735, Pusan, Korea aut Lee Jeong College of Pharmacy, Pusan National University, 609-735, Pusan, Korea aut Back Jin College of Pharmacy, Pusan National University, 609-735, Pusan, Korea aut Archives of Pharmacal Research Pharmaceutical Society of Korea 15/2(1992-06-01), 126-129 0253-6269 15:2<126 1992 15 12272 https://doi.org/10.1007/BF02974086 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02974086 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Han Suk College of Pharmacy, Pusan National University, 609-735, Pusan, Korea aut NATIONALLICENCE 700 1- Kim Min College of Pharmacy, Pusan National University, 609-735, Pusan, Korea aut NATIONALLICENCE 700 1- Park Yong College of Pharmacy, Pusan National University, 609-735, Pusan, Korea aut NATIONALLICENCE 700 1- Lee Jeong College of Pharmacy, Pusan National University, 609-735, Pusan, Korea aut NATIONALLICENCE 700 1- Back Jin College of Pharmacy, Pusan National University, 609-735, Pusan, Korea aut NATIONALLICENCE 773 0- Archives of Pharmacal Research Pharmaceutical Society of Korea 15/2(1992-06-01), 126-129 0253-6269 15:2<126 1992 15 12272 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer