caa a22 4500 469050284 CHVBK 20180323132828.0 cr unu---uuuuu 170328e19920601xx s 000 0 eng 10.1007/BF02974091 doi (NATIONALLICENCE)springer-10.1007/BF02974091 Effects of pertussis toxin on macrophage activation [Elektronische Daten] [Suck Lim, Nyeon An] The aim of this study was to evaluate capability of pertussis toxin(PT) to activate mouse macrophages. The investigations were undertaken to determine whether the role played by this toxin required the A-protomer of the toxin to ADP-ribosylate a guanine nucleotide binding protein (a Class I activity) or was dependent on the binding if B-oligomer of the toxin to the surface of target cells (a Class II activity). The results of these experiments have established that the mechanism of macrophage activation with PT seems to be dependent upon a Class II activity of the toxin. The Pharmaceutical Society of Korea, 1992 NAD glycohydrolase (EC 3.2.2.5) nationallicence pertussis toxin nationallicence murine macrophage nationallicence guanine nucleotide binding protein nationallicence Lim Suck College of Oriental Medicine, Taejeon University, 300-716, Taejion aut An Nyeon College of Pharmacy, Wonkwang University, 570-749, Iri, Korea aut Archives of Pharmacal Research Pharmaceutical Society of Korea 15/2(1992-06-01), 146-151 0253-6269 15:2<146 1992 15 12272 https://doi.org/10.1007/BF02974091 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02974091 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lim Suck College of Oriental Medicine, Taejeon University, 300-716, Taejion aut NATIONALLICENCE 700 1- An Nyeon College of Pharmacy, Wonkwang University, 570-749, Iri, Korea aut NATIONALLICENCE 773 0- Archives of Pharmacal Research Pharmaceutical Society of Korea 15/2(1992-06-01), 146-151 0253-6269 15:2<146 1992 15 12272 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer