caa a22 4500 469050578 CHVBK 20180323132829.0 cr unu---uuuuu 170328e19921201xx s 000 0 eng 10.1007/BF02493473 doi (NATIONALLICENCE)springer-10.1007/BF02493473 Foreign body entrapment in the esophagus of healthy subjects—A manometric and scintigraphic study [Elektronische Daten] [Hubert Stein, Werner Schwizer, Tom DeMeester, Mario Albertucci, Luigi Bonavina, Kelly Spires-Williams] Foreign body entrapment and mucosal injury caused by oral medications are increasingly reported to occur in the upper esophagus in apparently normal subjects. We performed esophageal manometry in 40 normal volunteers to determine whether a unique motility pattern in the upper third of the esophagus predisposes to entrapment of foreign bodies at this site; 18 normal volunteers also had transit scintigraphy of a gelatine capsule filled with a radionuclide. The esophageal body was divided into five consecutive segments starting proximally, with each segment corresponding to 20% of the total length. Amplitude, slope, and velocity of the esophageal contraction were markedly decreased in the second segment compared with the other segments. Entrapment and dissolution of a gelatine capsule occurred in 39% of volunteers in the proximal eosphagus correlating to the second segment, i.e., the segment with the lowest amplitude, slope, and velocity of esophageal contractions. The observation that wet swallows have greater amplitudes (P<0.01) and steeper slopes (P<0.05) than dry swallows explains why the occurrence of pill entrapment was reduced when taken with sufficient water. However, even with a water chaser of 120 mL, pill entrapment occurred at the second segment of the esophagus in 1 of 18 volunteers. The observed motility pattern in the proximal eosphagus provides a better explanation for the entrapment of foreign bodies at this site than compression of the esophagus by the left main stem bronchus, aortic arch, or left atrium as suggested by other investigators. Springer-Verlag New York Inc, 1992 Foreign body entrapment nationallicence Esophagus nationallicence Manometry nationallicence Transit scintigraphy nationallicence Deglutition nationallicence Deglutition disorders nationallicence Stein Hubert Department of Surgery, University of Southern California School of Medicine, 1510 San Pablo Street, Suite 514, CA 90033-4612, Los Angeles, USA aut Schwizer Werner Department of Surgery, Creighton University, Omaha, Nebraska, USA aut DeMeester Tom Department of Surgery, University of Southern California School of Medicine, 1510 San Pablo Street, Suite 514, CA 90033-4612, Los Angeles, USA aut Albertucci Mario Department of Surgery, Creighton University, Omaha, Nebraska, USA aut Bonavina Luigi Department of Surgery, Creighton University, Omaha, Nebraska, USA aut Spires-Williams Kelly Department of Nuclear Medicine, Creighton University, Omaha, Nebraska, USA aut Dysphagia Springer-Verlag 7/4(1992-12-01), 220-225 0179-051X 7:4<220 1992 7 455 https://doi.org/10.1007/BF02493473 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02493473 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Stein Hubert Department of Surgery, University of Southern California School of Medicine, 1510 San Pablo Street, Suite 514, CA 90033-4612, Los Angeles, USA aut NATIONALLICENCE 700 1- Schwizer Werner Department of Surgery, Creighton University, Omaha, Nebraska, USA aut NATIONALLICENCE 700 1- DeMeester Tom Department of Surgery, University of Southern California School of Medicine, 1510 San Pablo Street, Suite 514, CA 90033-4612, Los Angeles, USA aut NATIONALLICENCE 700 1- Albertucci Mario Department of Surgery, Creighton University, Omaha, Nebraska, USA aut NATIONALLICENCE 700 1- Bonavina Luigi Department of Surgery, Creighton University, Omaha, Nebraska, USA aut NATIONALLICENCE 700 1- Spires-Williams Kelly Department of Nuclear Medicine, Creighton University, Omaha, Nebraska, USA aut NATIONALLICENCE 773 0- Dysphagia Springer-Verlag 7/4(1992-12-01), 220-225 0179-051X 7:4<220 1992 7 455 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer