caa a22 4500 469053143 CHVBK 20180323132835.0 cr unu---uuuuu 170328e19920901xx s 000 0 eng 10.1007/BF01067922 doi (NATIONALLICENCE)springer-10.1007/BF01067922 Acoustic analysis in the differentiation of Parkinson's disease and major depression [Elektronische Daten] [Alastair Flint, Sandra Black, Irene Campbell-Taylor, Gillian Gailey, Carey Levinton] In its early stages, Parkinson's disease (P.D.) may be difficult to distinguish from major depression (M.D.) leading to inappropriate management. Both illnesses are characterized by psychomotor retardation. The neurovegetative symptoms used to diagnose M.D. are not specific and in P.D. may be due to the physical illness itself. Currently, differentiation of the two disorders relies on subjective clinical observation. Improved diagnostic accuracy based on more objective data is needed. To this end, this study used computerized acoustic analysis to contrast speech patterns in P.D. and M.D. The sample consisted of 30 P.D. patients without depression or dementia, 30 patients with uncomplicated M.D., and 31 normal controls, each 60 years of age or over. Of the acoustic variables studied, M.D. patients had significantly reduced rates of speech compared with P.D. patients. The data suggest that this temporal measure of speech may be useful in the differentiation of P.D. and M.D. Plenum Publishing Corporation, 1992 Flint Alastair Toronto General Hospital, Toronto, Canada aut Black Sandra Sunnybrook Health Science Centre, Toronto, Canada aut Campbell-Taylor Irene Sunnybrook Health Science Centre, Toronto, Canada aut Gailey Gillian Sunnybrook Health Science Centre, Toronto, Canada aut Levinton Carey Sunnybrook Health Science Centre, Toronto, Canada aut Journal of Psycholinguistic Research Kluwer Academic Publishers-Plenum Publishers 21/5(1992-09-01), 383-399 0090-6905 21:5<383 1992 21 10936 https://doi.org/10.1007/BF01067922 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01067922 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Flint Alastair Toronto General Hospital, Toronto, Canada aut NATIONALLICENCE 700 1- Black Sandra Sunnybrook Health Science Centre, Toronto, Canada aut NATIONALLICENCE 700 1- Campbell-Taylor Irene Sunnybrook Health Science Centre, Toronto, Canada aut NATIONALLICENCE 700 1- Gailey Gillian Sunnybrook Health Science Centre, Toronto, Canada aut NATIONALLICENCE 700 1- Levinton Carey Sunnybrook Health Science Centre, Toronto, Canada aut NATIONALLICENCE 773 0- Journal of Psycholinguistic Research Kluwer Academic Publishers-Plenum Publishers 21/5(1992-09-01), 383-399 0090-6905 21:5<383 1992 21 10936 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer