caa a22 4500 469054042 CHVBK 20180323132838.0 cr unu---uuuuu 170328e19920101xx s 000 0 eng 10.1007/BF01466272 doi (NATIONALLICENCE)springer-10.1007/BF01466272 Exercise-induced hypoxemia in athletes: Role of inadequate hyperventilation [Elektronische Daten] [Scott Powers, Daniel Martin, Michael Cicale, Nancy Collop, David Huang, David Criswell] Summary: These experiments examined the exercise-induced changes in pulmonary gas exchange in elite endurance athletes and tested the hypothesis that an inadequate hyperventilatory response might explain the large intersubject variability in arterial partial pressure of oxygen (P a02) during heavy exercise in this population. Twelve highly trained endurance cyclists [maximum oxygen consumption (VO2max) range = 65-77 ml·kg−1·min−1] performed a normoxic graded exercise test on a cycle ergometer toVO2max at sea level. During incremental exercise atVO2max 5 of the 12 subjects had ideal alveolar to arterial P02 gradients (P A-aO2) of above 5 kPa (range 5-5.7) and a decline from restingP aO2 (ΔP aO2) 2.4 kPa or above (range 2.4-2.7). In contrast, 4 subjects had a maximal exercise (P A-aO2) of 4.0-4.3 kPa with ΔP aO2 of 0.4-1.3 kPa while the remaining 3 subjects hadP A-aO2 of 4.3-5 kPa with ΔP aO2 between 1.7 and 2.0 kPa. The correlation between PAO2 andP aO2 atVO2max was 0.17. Further, the correlation between the ratio of ventilation to oxygen consumption VSP aO2 and arterial partial pressure of carbon dioxide VSP aO2 atVO2max was 0.17 and 0.34, respectively. These experiments demonstrate that heavy exercise results in significantly compromised pulmonary gas exchange in approximately 40% of the elite endurance athletes studied. These data do not support the hypothesis that the principal mechanism to explain this gas exchange failure is an inadequate hyperventilatory response. Springer-Verlag, 1992 Alveolar-arterial P O2 difference nationallicence Pulmonary gas exchange nationallicence V O2max nationallicence Hypoxia nationallicence Hyperoxia nationallicence Powers Scott Center for Exercise Science, Departments of Exercise and Sport Sciences, Physical Therapy, Medicine, and Physiology, University of Florida, 32611, Gainesville, FL, USA aut Martin Daniel Center for Exercise Science, Departments of Exercise and Sport Sciences, Physical Therapy, Medicine, and Physiology, University of Florida, 32611, Gainesville, FL, USA aut Cicale Michael Center for Exercise Science, Departments of Exercise and Sport Sciences, Physical Therapy, Medicine, and Physiology, University of Florida, 32611, Gainesville, FL, USA aut Collop Nancy Center for Exercise Science, Departments of Exercise and Sport Sciences, Physical Therapy, Medicine, and Physiology, University of Florida, 32611, Gainesville, FL, USA aut Huang David Center for Exercise Science, Departments of Exercise and Sport Sciences, Physical Therapy, Medicine, and Physiology, University of Florida, 32611, Gainesville, FL, USA aut Criswell David Center for Exercise Science, Departments of Exercise and Sport Sciences, Physical Therapy, Medicine, and Physiology, University of Florida, 32611, Gainesville, FL, USA aut European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 65/1(1992-01-01), 37-42 0301-5548 65:1<37 1992 65 421 https://doi.org/10.1007/BF01466272 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01466272 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Powers Scott Center for Exercise Science, Departments of Exercise and Sport Sciences, Physical Therapy, Medicine, and Physiology, University of Florida, 32611, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Martin Daniel Center for Exercise Science, Departments of Exercise and Sport Sciences, Physical Therapy, Medicine, and Physiology, University of Florida, 32611, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Cicale Michael Center for Exercise Science, Departments of Exercise and Sport Sciences, Physical Therapy, Medicine, and Physiology, University of Florida, 32611, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Collop Nancy Center for Exercise Science, Departments of Exercise and Sport Sciences, Physical Therapy, Medicine, and Physiology, University of Florida, 32611, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Huang David Center for Exercise Science, Departments of Exercise and Sport Sciences, Physical Therapy, Medicine, and Physiology, University of Florida, 32611, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Criswell David Center for Exercise Science, Departments of Exercise and Sport Sciences, Physical Therapy, Medicine, and Physiology, University of Florida, 32611, Gainesville, FL, USA aut NATIONALLICENCE 773 0- European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 65/1(1992-01-01), 37-42 0301-5548 65:1<37 1992 65 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer