caa a22 4500 469054174 CHVBK 20180323132838.0 cr unu---uuuuu 170328e19921101xx s 000 0 eng 10.1007/BF00602360 doi (NATIONALLICENCE)springer-10.1007/BF00602360 Differential mobilization of leucocyte and lymphocyte subpopulations into the circulation during endurance exercise [Elektronische Daten] [Holger Gabriel, Lothar Schwarz, Petra Born, Wilfried Kindermann] Summary: A total of 14 healthy subjects [means (SD): 27.6 (3.8) years; body mass 77.8 (6.6) kg; height 183 (6) cm] performed endurance exercise to exhaustion at 100% of the individual anaerobic threshold (Than) on a cycle ergometer (mean workload 207 (55) W; lactate concentrations 3.4 (1.2) mmol · l−1; duration 83.8 (22.2) min, including 5 min at 50% of individual Than). Leucocyte subpopulations were measured by flow cytometry and catecholamines by radioimmunological methods. Blood samples were taken before and several times during exercise. Values were corrected for plasma volume changes and analysed using ANOVA for repeated measures. During the first 10 min of exercise, of all cell subpopulations the natural killer cells (CD3−CD16/CD56+) increased the most (229%). Also CD3÷CD16/CD56+ (84%), CD8÷CD45RO− (69%) cells, eosinophils (36%) and monocytes (62%) increased rapidly during thattime.CD3+, CD3+HLA-DR+, CD4+CD45RO+, CD4+CD45RO−, CD8+CD45RO÷ and CD19+ cells either did not increase or increased only slightly during exercise. Adrenaline and noradrenaline increased nearly linearly by 36% and 77% respectively at 10 min exercise. The increase of natural killer cells and heart rates between rest and 10 min of exercise correlated significantly (r=0.576,P=0.031). We conclude that natural killer cells, cytotoxic, non-MHC-restricted T-cells, monocytes and eosinophils are mobilized rapidly during the first minutes of endurance exercise. Both catecholamines and increased blood flow are likely to contribute this effect. Springer-Verlag, 1992 Leucocyte subpopulations nationallicence Natural killer cells nationallicence Catecholamines nationallicence Endurance exercise nationallicence Gabriel Holger Institute of Sports and Performance Medicine, University of Saarland, W-6600, Saarbrücken, Germany aut Schwarz Lothar Institute of Sports and Performance Medicine, University of Saarland, W-6600, Saarbrücken, Germany aut Born Petra Institute of Sports and Performance Medicine, University of Saarland, W-6600, Saarbrücken, Germany aut Kindermann Wilfried Institute of Sports and Performance Medicine, University of Saarland, W-6600, Saarbrücken, Germany aut European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 65/6(1992-11-01), 529-534 0301-5548 65:6<529 1992 65 421 https://doi.org/10.1007/BF00602360 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00602360 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gabriel Holger Institute of Sports and Performance Medicine, University of Saarland, W-6600, Saarbrücken, Germany aut NATIONALLICENCE 700 1- Schwarz Lothar Institute of Sports and Performance Medicine, University of Saarland, W-6600, Saarbrücken, Germany aut NATIONALLICENCE 700 1- Born Petra Institute of Sports and Performance Medicine, University of Saarland, W-6600, Saarbrücken, Germany aut NATIONALLICENCE 700 1- Kindermann Wilfried Institute of Sports and Performance Medicine, University of Saarland, W-6600, Saarbrücken, Germany aut NATIONALLICENCE 773 0- European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 65/6(1992-11-01), 529-534 0301-5548 65:6<529 1992 65 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer