caa a22 4500 469054522 CHVBK 20180323132839.0 cr unu---uuuuu 170328e19920701xx s 000 0 eng 10.1007/BF00868136 doi (NATIONALLICENCE)springer-10.1007/BF00868136 Active and inactive renin after exercise [Elektronische Daten] [M. Ikeda, M. Matsusaki, A. Kinoshita, M. Koga, M. Ideishi, M. Sasaguri, H. Tanaka, M. Shindo, K. Arakawa] Summary: The effects of graded exercise on plasma concentrations of active and inactive renin were studied in seven healthy men. Exercise was performed on a cycle ergometer at four different exercise intensities (corresponding to 30%, 50%, 80% and 87% of $$\dot VO_{2 max} $$ ) for 10 min each. Concentrations of active renin and total renin after activation by trypsin were measured by direct immunoradiometric assay. Non-trypsin-activated renin concentration (inactive) was obtained by subtraction. Active renin concentrations at 30%, 50%, 80% and 87% of $$\dot VO_{2 max} $$ were 1.2, 1.9, 3.1 and 4.6 times higher than the control concentration, respectively. Similar increases in plasma renin concentration, determined by conventional enzymatic assay, were observed at every stage. In contrast, changes in inactive renin concentration were not significant at any stage. Significant increases in noradrenaline concentration were found at every exercise stage, but adrenaline, aldosterone and lactate concentrations were significantly elevated only after exercise at 50%, 80% and 87% of $$\dot VO_{2 max} $$ . The similarity between the changes in concentration of active renin and noradrenaline would suggest that sympathetic nerve activity may have been responsible either for the release of active renin or for the conversion of inactive renin to its active form in the kidney. Springer-Verlag, 1992 Active renin nationallicence Inactive renin nationallicence Lactate threshold nationallicence Noradrenaline nationallicence Ikeda M. Department of Internal Medicine, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-01, Fukuoka, Japan aut Matsusaki M. Department of Internal Medicine, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-01, Fukuoka, Japan aut Kinoshita A. Department of Internal Medicine, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-01, Fukuoka, Japan aut Koga M. Department of Internal Medicine, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-01, Fukuoka, Japan aut Ideishi M. Department of Internal Medicine, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-01, Fukuoka, Japan aut Sasaguri M. Department of Internal Medicine, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-01, Fukuoka, Japan aut Tanaka H. Department of Exercise Physiology, School of Physical Education, Fukuoka University, 7-45-1 Nanakuma, Jonanku, 814-01, Fukuoka, Japan aut Shindo M. Department of Exercise Physiology, School of Physical Education, Fukuoka University, 7-45-1 Nanakuma, Jonanku, 814-01, Fukuoka, Japan aut Arakawa K. Department of Internal Medicine, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-01, Fukuoka, Japan aut European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 65/4(1992-07-01), 331-334 0301-5548 65:4<331 1992 65 421 https://doi.org/10.1007/BF00868136 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00868136 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ikeda M. Department of Internal Medicine, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-01, Fukuoka, Japan aut NATIONALLICENCE 700 1- Matsusaki M. Department of Internal Medicine, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-01, Fukuoka, Japan aut NATIONALLICENCE 700 1- Kinoshita A. Department of Internal Medicine, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-01, Fukuoka, Japan aut NATIONALLICENCE 700 1- Koga M. Department of Internal Medicine, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-01, Fukuoka, Japan aut NATIONALLICENCE 700 1- Ideishi M. Department of Internal Medicine, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-01, Fukuoka, Japan aut NATIONALLICENCE 700 1- Sasaguri M. Department of Internal Medicine, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-01, Fukuoka, Japan aut NATIONALLICENCE 700 1- Tanaka H. Department of Exercise Physiology, School of Physical Education, Fukuoka University, 7-45-1 Nanakuma, Jonanku, 814-01, Fukuoka, Japan aut NATIONALLICENCE 700 1- Shindo M. Department of Exercise Physiology, School of Physical Education, Fukuoka University, 7-45-1 Nanakuma, Jonanku, 814-01, Fukuoka, Japan aut NATIONALLICENCE 700 1- Arakawa K. Department of Internal Medicine, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-01, Fukuoka, Japan aut NATIONALLICENCE 773 0- European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 65/4(1992-07-01), 331-334 0301-5548 65:4<331 1992 65 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer