caa a22 4500 469054670 CHVBK 20180323132840.0 cr unu---uuuuu 170328e19921101xx s 000 0 eng 10.1007/BF00243515 doi (NATIONALLICENCE)springer-10.1007/BF00243515 Effect of moderate exercise on rat T-cells [Elektronische Daten] [A. Ferry, P. Rieu, F. Laziri, A. El Habazi, C. Le Page, M. Rieu] Summary: The aim of this study was a detailed examination of the effects of moderate exercise on T-cells in adult male Wistar rats. The T-cell populations were compared in sedentary rats (C, n = 5) and in rats trained for 4 weeks on a treadmill (30-60 min·day−1, 6 days·week−1, 20-30 m·min−1) and sacrificed at rest (Trest, n=5). In the T-rest rats, there were higher percentages of CD4+CD8−, CD4− CD8 + and CD4 − CD8 −thymocytes (P<0.05, P<0.05 and P<0.01 respectively) and of CD4−CD8 + splenocytes (P< 0.01), and a lower percentage of CD4−CD8+ cells in the lymph nodes (P<0.01). Compared with T-rest or C rats, trained rats (n = 5) or untrained rats (n = 5) sacrificed immediately after a running session (60 min, 30 m·min−1) had a higher percentage of mononucleated cells CD4 + CD8 -in the blood (P<0.05 and P<0.01). Lastly, compared with C rats, rats (n=5) sacrificed immediately after their 5th day of training (30-60 min·day−1) presented a higher total splenocyte population (P<0.05) and greater in vitro production of T-cell growth factor (interleukin 2 + interleucin 4) by splenocytes in response to a mitogen (P<0.01). These results would indicate that moderate endurance training modifies the cellular composition of lymphoid organs, without impairing the in vitro functions of T-cells. Springer-Verlag, 1992 Physical training nationallicence Acute exercise nationallicence Lymphocyte nationallicence T-cell growth factor nationallicence Thymus nationallicence Stress nationallicence Ferry A. Laboratoire de Physiologie des Adaptations, U.F.R. Cochin Port-Royal, Université Paris V, 24 rue du Faubourg Saint-Jacques, F-75014, Paris, France aut Rieu P. Institut National Scientifique de la Recherche Médicale, Unité 90, F-75015, Paris, France aut Laziri F. Laboratoire de Physiologie des Adaptations, U.F.R. Cochin Port-Royal, Université Paris V, 24 rue du Faubourg Saint-Jacques, F-75014, Paris, France aut El Habazi A. Laboratoire de Physiologie des Adaptations, U.F.R. Cochin Port-Royal, Université Paris V, 24 rue du Faubourg Saint-Jacques, F-75014, Paris, France aut Le Page C. Laboratoire de Physiologie des Adaptations, U.F.R. Cochin Port-Royal, Université Paris V, 24 rue du Faubourg Saint-Jacques, F-75014, Paris, France aut Rieu M. Laboratoire de Physiologie des Adaptations, U.F.R. Cochin Port-Royal, Université Paris V, 24 rue du Faubourg Saint-Jacques, F-75014, Paris, France aut European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 65/5(1992-11-01), 464-468 0301-5548 65:5<464 1992 65 421 https://doi.org/10.1007/BF00243515 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00243515 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ferry A. Laboratoire de Physiologie des Adaptations, U.F.R. Cochin Port-Royal, Université Paris V, 24 rue du Faubourg Saint-Jacques, F-75014, Paris, France aut NATIONALLICENCE 700 1- Rieu P. Institut National Scientifique de la Recherche Médicale, Unité 90, F-75015, Paris, France aut NATIONALLICENCE 700 1- Laziri F. Laboratoire de Physiologie des Adaptations, U.F.R. Cochin Port-Royal, Université Paris V, 24 rue du Faubourg Saint-Jacques, F-75014, Paris, France aut NATIONALLICENCE 700 1- El Habazi A. Laboratoire de Physiologie des Adaptations, U.F.R. Cochin Port-Royal, Université Paris V, 24 rue du Faubourg Saint-Jacques, F-75014, Paris, France aut NATIONALLICENCE 700 1- Le Page C. Laboratoire de Physiologie des Adaptations, U.F.R. Cochin Port-Royal, Université Paris V, 24 rue du Faubourg Saint-Jacques, F-75014, Paris, France aut NATIONALLICENCE 700 1- Rieu M. Laboratoire de Physiologie des Adaptations, U.F.R. Cochin Port-Royal, Université Paris V, 24 rue du Faubourg Saint-Jacques, F-75014, Paris, France aut NATIONALLICENCE 773 0- European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 65/5(1992-11-01), 464-468 0301-5548 65:5<464 1992 65 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer