caa a22 4500 469054875 CHVBK 20180323132840.0 cr unu---uuuuu 170328e19920301xx s 000 0 eng 10.1007/BF00705076 doi (NATIONALLICENCE)springer-10.1007/BF00705076 Increased working capacity with hyperoxia in humans [Elektronische Daten] [J. Plet, P. Pedersen, F. Jensen, J. Hansen] Summary: The purpose of the study was to examine the influence of oxygen-breathing on maximal oxygen uptake ( $$\dot V$$ O2max) and submaximal endurance performance. Six young women and five men rode a cycle-ergometer while breathing compressed air (normoxia, NOX) or a 55% O2 in N2 mixture (hyperoxia, HOX). The $$\dot V$$ O2max increased significantly by 12% (P<0.01) with HOX in the women but not in the men (+4%; nonsignificant). Maximal heart rate was also increased with HOX in the women but not in the men. Endurance time during work to -exhaustion at 80% of normoxic $$\dot V$$ O2max was 41% longer in HOX than in NOX (P<0.025) with no significant difference between the men and the women. The variation among individuals was large. The oxygen uptake and respiratory quotient were not different in the two endurance tests, but pulmonary ventilation ( $$\dot V$$ E) and blood lactate concentration were lower in HOX than in NOX, especially during the latter part of the task. Plasma base deficit (BDpi) increased initially by 3.5 mmol · l−1 during HOX and then stabilized. In NOX, a continuous increase was seen and the change was more than twice as large. Relative to BDpl, $$\dot V$$ E was higher in HOX than in NOX indicating a more efficient ventilatory compensation of the metabolic acidosis. The reduced ventilatory demand and lower metabolic acidosis in HOX in combination with lower relative exercise intensity may have contributed to the longer time to exhaustion. However, the pattern of individual variation suggested that other mechanisms were also involved. Springer-Verlag, 1995 Base deficit nationallicence Endurance performance nationallicence Hyperoxia nationallicence Limiting factors nationallicence Men and women nationallicence Maximal oxygen consumption nationallicence Plet J. Institute of Physical Education, Odense University, Campusvej 55, DK-5230, Odense M, Denmark aut Pedersen P. Institute of Physical Education, Odense University, Campusvej 55, DK-5230, Odense M, Denmark aut Jensen F. Institute of Biology, Odense University, Campusvej 55, DK-5230, Odense M, Denmark aut Hansen J. Institute of Biochemistry, Odense University, Campusvej 55, DK-5230, Odense M, Denmark aut European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 65/2(1992-03-01), 171-177 0301-5548 65:2<171 1992 65 421 https://doi.org/10.1007/BF00705076 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00705076 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Plet J. Institute of Physical Education, Odense University, Campusvej 55, DK-5230, Odense M, Denmark aut NATIONALLICENCE 700 1- Pedersen P. Institute of Physical Education, Odense University, Campusvej 55, DK-5230, Odense M, Denmark aut NATIONALLICENCE 700 1- Jensen F. Institute of Biology, Odense University, Campusvej 55, DK-5230, Odense M, Denmark aut NATIONALLICENCE 700 1- Hansen J. Institute of Biochemistry, Odense University, Campusvej 55, DK-5230, Odense M, Denmark aut NATIONALLICENCE 773 0- European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 65/2(1992-03-01), 171-177 0301-5548 65:2<171 1992 65 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer