caa a22 4500 469055146 CHVBK 20180323132841.0 cr unu---uuuuu 170328e19921101xx s 000 0 eng 10.1007/BF00843760 doi (NATIONALLICENCE)springer-10.1007/BF00843760 Studies on the immediate and delayed leucocytosis elicited by brief (30-min) strenuous exercise [Elektronische Daten] [D. McCarthy, I. Macdonald, M. Grant, M. Marbut, M. Watling, S. Nicholson, J. Deeks, A. Wade, J. Perry] Summary: Eight healthy male volunteers exercised for two 30-min sessions starting 3 h apart on an electronically braked cycle ergometer at a work load (mean 155.9 W, SD 33.4 W) which required an oxygen consumption that was 70% of their maximal rate of oxygen uptake. Venous blood samples were taken through an indwelling cannula over a period of 6 h beginning shortly before the first bout of exercise and were analysed for routine haematological parameters and for lactate, noradrenaline, adrenaline and cortisol. Both bouts of exercise induced an immediate leucocytosis due to rises in lymphocytes and neutrophils but only the first exercise bout induced a substantial delayed neutrophilia. In at least five subjects, changes in lymphocyte and platelet numbers were correlated (Spearman's rank procedure,P<0.05) with simultaneous changes in the plasma concentrations of lactate, noradrenaline and adrenaline over the 6-h period studied. Increases in the plasma concentration of cortisol due to exercise correlated positively with the percentage changes in neutrophil numbers at 3 h and 6 h. These results are consistent with the suggestion that the immediate and delayed leucocytosis induced by exercise are mediated respectively by catecholamine and by cortisol. Springer-Verlag, 1992 Leucocytes nationallicence Lymphopenia nationallicence Granulocytosis nationallicence Catecholamines nationallicence Cortisol nationallicence McCarthy D. School of Biological Sciences, Queen Mary and Westfield College, E1 4NS, London, UK aut Macdonald I. Department of Physiology and Pharmacology, University of Nottingham, Queens Medical Centre, NG7 2UH, Nottingham, UK aut Grant M. Department of Sports Medicine, London Hospital Medical College, E1 2AD, London, UK aut Marbut M. Department of Sports Medicine, London Hospital Medical College, E1 2AD, London, UK aut Watling M. Department of Sports Medicine, London Hospital Medical College, E1 2AD, London, UK aut Nicholson S. Department of Gynaecology and Obstetrics, St Thomas' Hospital, SE1 7EH, London, UK aut Deeks J. Department of Epidemiology and Statistics, London Hospital Medical College, E1 2AD, London, UK aut Wade A. Department of Sports Medicine, London Hospital Medical College, E1 2AD, London, UK aut Perry J. Department of Rheumatology, The Royal London Hospital, E1 1BB, London, UK aut European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 64/6(1992-11-01), 513-517 0301-5548 64:6<513 1992 64 421 https://doi.org/10.1007/BF00843760 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00843760 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- McCarthy D. School of Biological Sciences, Queen Mary and Westfield College, E1 4NS, London, UK aut NATIONALLICENCE 700 1- Macdonald I. Department of Physiology and Pharmacology, University of Nottingham, Queens Medical Centre, NG7 2UH, Nottingham, UK aut NATIONALLICENCE 700 1- Grant M. Department of Sports Medicine, London Hospital Medical College, E1 2AD, London, UK aut NATIONALLICENCE 700 1- Marbut M. Department of Sports Medicine, London Hospital Medical College, E1 2AD, London, UK aut NATIONALLICENCE 700 1- Watling M. Department of Sports Medicine, London Hospital Medical College, E1 2AD, London, UK aut NATIONALLICENCE 700 1- Nicholson S. Department of Gynaecology and Obstetrics, St Thomas' Hospital, SE1 7EH, London, UK aut NATIONALLICENCE 700 1- Deeks J. Department of Epidemiology and Statistics, London Hospital Medical College, E1 2AD, London, UK aut NATIONALLICENCE 700 1- Wade A. Department of Sports Medicine, London Hospital Medical College, E1 2AD, London, UK aut NATIONALLICENCE 700 1- Perry J. Department of Rheumatology, The Royal London Hospital, E1 1BB, London, UK aut NATIONALLICENCE 773 0- European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 64/6(1992-11-01), 513-517 0301-5548 64:6<513 1992 64 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer