caa a22 4500 469055340 CHVBK 20180323132842.0 cr unu---uuuuu 170328e19920501xx s 000 0 eng 10.1007/BF00626282 doi (NATIONALLICENCE)springer-10.1007/BF00626282 Effects of anabolic steroids and high intensity exercise on rat skeletal muscle fibres and capillarization [Elektronische Daten] A morphometric study [J. Dimauro, R. Balnave, C. Shorey] Summary: The effects were investigated of high intensity short duration exercise and anabolic steroid treatment on the medial gastrocnemius muscle of female rats. Twelve rats were divided equally into four groups, exercise with and without steroid administration and sedentary with and without steroid administration. Animals were made to swim for 5 weeks, 6 days·week−1. Muscle fibres were classified as slow-twitch (ST), fast-twitch oxidative glycolytic (FOG) and fast-twitch glycolytic (FG). Muscle fibre size was measured as the equivalent circle diameter. Exercise (P<0.001) and steroid (P<0.05) treatments alone, significantly elevated FOG and decreased FG fibre proportions. Overall proportions of fast-twitch and ST muscle fibres did not vary with any of the treatments. Significant differences in the proportion of muscle fibres were found to exist between different areas within the gastrocnemius muscle (P<0.05). Exercise and steroid treatments alone did not alter muscle fibre diameters. Combined exercise and steroid treatments did significantly increase ST fibre diameters (P<0.05). Exercise only treatment resulted in significant increases in the number of capillaries surrounding ST fibre (P<0.05) and FOG fibre (P<0.01) types. In conclusion the main finding of this study indicated that anabolic steroids in conjunction with high intensity swimming instigated ST fibre hypertrophy. Exercise and steroid only treatments significantly elevated FOG fibre proportions while FG fibre proportions diminished. Exercise only treatment resulted in significant increases in the number of capillaries surrounding both ST and FOG fibre types. Springer-Verlag, 1992 Anabolic steroids nationallicence Exercise nationallicence Morphometry nationallicence Capillaries nationallicence Skeletal muscle nationallicence Dimauro J. Cumberland College of Health Sciences, University of Sydney, 2006, Sydney, Australia aut Balnave R. Cumberland College of Health Sciences, University of Sydney, 2006, Sydney, Australia aut Shorey C. Department of Histology and Embryology, University of Sydney, 2006, Sydney, Australia aut European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 64/3(1992-05-01), 204-212 0301-5548 64:3<204 1992 64 421 https://doi.org/10.1007/BF00626282 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00626282 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dimauro J. Cumberland College of Health Sciences, University of Sydney, 2006, Sydney, Australia aut NATIONALLICENCE 700 1- Balnave R. Cumberland College of Health Sciences, University of Sydney, 2006, Sydney, Australia aut NATIONALLICENCE 700 1- Shorey C. Department of Histology and Embryology, University of Sydney, 2006, Sydney, Australia aut NATIONALLICENCE 773 0- European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 64/3(1992-05-01), 204-212 0301-5548 64:3<204 1992 64 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer