caa a22 4500 469055359 CHVBK 20180323132842.0 cr unu---uuuuu 170328e19920501xx s 000 0 eng 10.1007/BF00626289 doi (NATIONALLICENCE)springer-10.1007/BF00626289 Inter-relationships between pituitary-adrenal hormones and catecholamines during a 6-day Nordic ski race [Elektronische Daten] [Nicole Fellmann, Mario Bedu, Gil Boudet, Martine Mage, Marcel Sagnol, Jean-Marc Pequignot, Bruno Claustrat, Jocelyne Brun, Liliane Peyrin, Jean Coudert] Summary: The aim of the study was to investigate the inter-relationships between pituitary-adrenal hormones and catecholamines during a prolonged competition over 6 days. Plasma adrenocorticotropic hormone (ACTH), cortisol (C), β-endorphin (βEP), free and sulphated adrenaline (A) and noradrenaline (NA) were measured in 11 volunteer male subjects during a national Nordic-ski race (323 km). Blood samples were obtained before the competition in the evening as control (D0), and before and after each day's racing (D1-D6). The mean daily heart rate (f c) was calculated fromf c values recorded every minute during the race. The results showed the following: changes in meanf c [from 147 (SEM 3) to 156 (SEM 3) beats · min−1 according to the day] were not significant during the race. Diurnal variations in ACTH, βEP and C were no longer apparent after the race: evening levels were higher than their respective D0 values during the race, except on D3 when there was a lack of response to exercise in the three hormones. Unlike ACTH and βEP, pre- and postexercise C values on D1 and D2 were higher than those on the subsequent days (P<0.001). In contrast, there was a progressive accumulation of A and NA in pre-and postrace concentrations which reached a plateau in about 4 days. Positive correlations between exercise responses in ACTH, C and βEP were found especially on D3 and D6 (P<0.001) but there were no significant correlations between catecholamines and the other three hormones. Thus, prolonged competition over 6 days evoked different control mechanisms for hormones of the pituitary-adrenal axis and catecholamines. A sustained catecholamine release and sympathetic activation induced a progressive NA and A accumulation during the race. In contrast, the lack of a response to exercise in ACTH, βEP and C on D3 suggested a dissociated central command for pituitary axis hormones and sympathetic adrenal activation. On the following days, the response to a lack of exercise, in spite of ACTH stimulation, may have reflected an adaptation of adrenal glands to prolonged stress. Springer-Verlag, 1992 ACTH nationallicence Cortisol nationallicence β-Endorphin nationallicence Epinephrine nationallicence Norepinephrine nationallicence Fellmann Nicole Laboratoire de Physiologie - Biologie du Sport, Faculté de Médecine, F-63000, Clermont-Ferrand, France aut Bedu Mario Laboratoire de Physiologie - Biologie du Sport, Faculté de Médecine, F-63000, Clermont-Ferrand, France aut Boudet Gil Laboratoire de Physiologie - Biologie du Sport, Faculté de Médecine, F-63000, Clermont-Ferrand, France aut Mage Martine Laboratoire de Physiologie - Biologie du Sport, Faculté de Médecine, F-63000, Clermont-Ferrand, France aut Sagnol Marcel Centre National de la Recherche Scientifique UA 1196 Catécholamines Laboratoire de Physiologie, Faculté de Médecine Grange-Blanche, 8 Avenue Rockefeller, F-69373, Lyon, France aut Pequignot Jean-Marc Centre National de la Recherche Scientifique UA 1196 Catécholamines Laboratoire de Physiologie, Faculté de Médecine Grange-Blanche, 8 Avenue Rockefeller, F-69373, Lyon, France aut Claustrat Bruno Centre de Médecine Nucléaire, Hôpital Neuro-Cardiologique, 59, Boulevard Pinel, F-69003, Lyon, France aut Brun Jocelyne Centre de Médecine Nucléaire, Hôpital Neuro-Cardiologique, 59, Boulevard Pinel, F-69003, Lyon, France aut Peyrin Liliane Centre National de la Recherche Scientifique UA 1196 Catécholamines Laboratoire de Physiologie, Faculté de Médecine Grange-Blanche, 8 Avenue Rockefeller, F-69373, Lyon, France aut Coudert Jean Laboratoire de Physiologie - Biologie du Sport, Faculté de Médecine, F-63000, Clermont-Ferrand, France aut European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 64/3(1992-05-01), 258-265 0301-5548 64:3<258 1992 64 421 https://doi.org/10.1007/BF00626289 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00626289 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fellmann Nicole Laboratoire de Physiologie - Biologie du Sport, Faculté de Médecine, F-63000, Clermont-Ferrand, France aut NATIONALLICENCE 700 1- Bedu Mario Laboratoire de Physiologie - Biologie du Sport, Faculté de Médecine, F-63000, Clermont-Ferrand, France aut NATIONALLICENCE 700 1- Boudet Gil Laboratoire de Physiologie - Biologie du Sport, Faculté de Médecine, F-63000, Clermont-Ferrand, France aut NATIONALLICENCE 700 1- Mage Martine Laboratoire de Physiologie - Biologie du Sport, Faculté de Médecine, F-63000, Clermont-Ferrand, France aut NATIONALLICENCE 700 1- Sagnol Marcel Centre National de la Recherche Scientifique UA 1196 Catécholamines Laboratoire de Physiologie, Faculté de Médecine Grange-Blanche, 8 Avenue Rockefeller, F-69373, Lyon, France aut NATIONALLICENCE 700 1- Pequignot Jean-Marc Centre National de la Recherche Scientifique UA 1196 Catécholamines Laboratoire de Physiologie, Faculté de Médecine Grange-Blanche, 8 Avenue Rockefeller, F-69373, Lyon, France aut NATIONALLICENCE 700 1- Claustrat Bruno Centre de Médecine Nucléaire, Hôpital Neuro-Cardiologique, 59, Boulevard Pinel, F-69003, Lyon, France aut NATIONALLICENCE 700 1- Brun Jocelyne Centre de Médecine Nucléaire, Hôpital Neuro-Cardiologique, 59, Boulevard Pinel, F-69003, Lyon, France aut NATIONALLICENCE 700 1- Peyrin Liliane Centre National de la Recherche Scientifique UA 1196 Catécholamines Laboratoire de Physiologie, Faculté de Médecine Grange-Blanche, 8 Avenue Rockefeller, F-69373, Lyon, France aut NATIONALLICENCE 700 1- Coudert Jean Laboratoire de Physiologie - Biologie du Sport, Faculté de Médecine, F-63000, Clermont-Ferrand, France aut NATIONALLICENCE 773 0- European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 64/3(1992-05-01), 258-265 0301-5548 64:3<258 1992 64 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer