caa a22 4500 469055871 CHVBK 20180323132843.0 cr unu---uuuuu 170328e19920301xx s 000 0 eng 10.1007/BF00717949 doi (NATIONALLICENCE)springer-10.1007/BF00717949 Blood flow and muscle bio-energetics by31P-nuclear magnetic resonance after local cold acclimation [Elektronische Daten] [Gustave Savourey, Lionel Clerc, Andre Vallerand, Georges Leftheriotis, Henri Mehier, Jacques Bittel] Summary: To clarify the origin of local cold adaptation and to define precisely its influence on muscle bio-energetics during local exercise, five subjects were subjected to repeated 5°C cold water immersion of the right hand and forearm. The first aim of our investigation was therefore carried out by measuring local skin temperatures and peripheral blood flow during a cold hand test (5°C, 5 min) followed by a 10-min recovery period. The31P by nuclear magnetic resonance (31PNMR) muscle bio-energetic changes, indicating possible heat production changes, were measured during the recovery period. The second aim of our investigation was carried out by measuring31PNMR muscle bioenergetics during handgrip exercise (10% of the maximal voluntary contraction for 5 min followed by a 10-min recovery period) performed both at a comfortable ambient temperature (22°C; E) and after a cold hand test (EC), before and after local cold adaptation. Local cold adaptation, confirmed by warmer skin temperatures of the extremities (+30%,P<0.05), was related more to an increased peripheral blood flow, as shown by the smaller decrease in systolic peak [−245 (SEM 30) Hz vs −382 (SEM 95) Hz,P<0.05] than to a change in local heat production, because muscle bioenergetics did not vary. Acute local cold immersion decreased the inorganic phosphate: phosphocreatine (PC) ratio during EC compared to E [+0.006 (SEM 0.010) vs +0.078 (SEM 0.002) before acclimation and +0.029 (SEM 0.002) vs +0.090 (SEM 0.002) after acclimation respectively, P<0.05] without significant change in the PC:β-adenosine triphosphate ratio and pH. Local adaptation did not modify these results statistically. The recovery of PC during E increased after acclimation [9.0 (SEM 0.2) min vs 3.0 (SEM 0.4) min,P<0.05]. These results suggested that local cold adaptation is related more to peripheral blood flow changes than to increased metabolic heat production in the muscle. Springer-Verlag, 1992 31P by nuclear magnetic resonance nationallicence Muscle bio-energetics nationallicence Local cold adaptation nationallicence Savourey Gustave Centre de Recherches du Service de Santé des Armées, Unité de Thermophysiologie, 24, avenue des Maquis du Grésivaudan, B.P. 87, F-38 702, La Tronche Cédex, France aut Clerc Lionel Centre de Recherches du Service de Santé des Armées, Unité de Thermophysiologie, 24, avenue des Maquis du Grésivaudan, B.P. 87, F-38 702, La Tronche Cédex, France aut Vallerand Andre Defence and Civil Institute of Environmental Medicine, 1133 Sheppard Ave. W. North York Ontario, M3M3B9, Canada aut Leftheriotis Georges Centre de Recherches du Service de Santé des Armées, Unité de Thermophysiologie, 24, avenue des Maquis du Grésivaudan, B.P. 87, F-38 702, La Tronche Cédex, France aut Mehier Henri Laboratoire de RMN Hopital de Chamonix, B.P. 88, F-74 400, Chamonix, France aut Bittel Jacques Centre de Recherches du Service de Santé des Armées, Unité de Thermophysiologie, 24, avenue des Maquis du Grésivaudan, B.P. 87, F-38 702, La Tronche Cédex, France aut European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 64/2(1992-03-01), 127-133 0301-5548 64:2<127 1992 64 421 https://doi.org/10.1007/BF00717949 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00717949 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Savourey Gustave Centre de Recherches du Service de Santé des Armées, Unité de Thermophysiologie, 24, avenue des Maquis du Grésivaudan, B.P. 87, F-38 702, La Tronche Cédex, France aut NATIONALLICENCE 700 1- Clerc Lionel Centre de Recherches du Service de Santé des Armées, Unité de Thermophysiologie, 24, avenue des Maquis du Grésivaudan, B.P. 87, F-38 702, La Tronche Cédex, France aut NATIONALLICENCE 700 1- Vallerand Andre Defence and Civil Institute of Environmental Medicine, 1133 Sheppard Ave. W. North York Ontario, M3M3B9, Canada aut NATIONALLICENCE 700 1- Leftheriotis Georges Centre de Recherches du Service de Santé des Armées, Unité de Thermophysiologie, 24, avenue des Maquis du Grésivaudan, B.P. 87, F-38 702, La Tronche Cédex, France aut NATIONALLICENCE 700 1- Mehier Henri Laboratoire de RMN Hopital de Chamonix, B.P. 88, F-74 400, Chamonix, France aut NATIONALLICENCE 700 1- Bittel Jacques Centre de Recherches du Service de Santé des Armées, Unité de Thermophysiologie, 24, avenue des Maquis du Grésivaudan, B.P. 87, F-38 702, La Tronche Cédex, France aut NATIONALLICENCE 773 0- European Journal of Applied Physiology and Occupational Physiology Springer-Verlag 64/2(1992-03-01), 127-133 0301-5548 64:2<127 1992 64 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer