caa a22 4500 469056673 CHVBK 20180323132845.0 cr unu---uuuuu 170328e19920601xx s 000 0 eng 10.1163/156856792X00128 doi (NATIONALLICENCE)springer-10.1163/156856792X00128 Chandrasekhar S. Department of Organic Chemistry, Indian Institute of Science, 560 012, Bangalore, India aut The principle of microscopic reversibility in organic chemistry - a critique [Elektronische Daten] [S. Chandrasekhar] Conclusion: The principle of microscopic reversibility is one of the few generalising principles used in organic chemistry which have their roots in the fundamental laws of thermodynamics. It has, therefore, been highly popular. However, although the principle has some important uses, its general application is not without pitfalls. The principle is easy to misunderstand and to misapply: indeed, some of its formulations are semantically dubious. The principle is most dangerous when used as a charm, for it is more subtle than some of its formulations suggest. But above all, the principle may not be used for deducing or disproving the mechanism of a reaction, except when the mechanism in the reverse direction is known independently. For, such use is, perhaps, the deadliest misapplication. Springer, 1992 Research on Chemical Intermediates Springer Netherlands 17/2(1992-06-01), 173-209 0922-6168 17:2<173 1992 17 11164 https://doi.org/10.1163/156856792X00128 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1163/156856792X00128 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Chandrasekhar S. Department of Organic Chemistry, Indian Institute of Science, 560 012, Bangalore, India aut NATIONALLICENCE 773 0- Research on Chemical Intermediates Springer Netherlands 17/2(1992-06-01), 173-209 0922-6168 17:2<173 1992 17 11164 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer