caa a22 4500 469060239 CHVBK 20180323132855.0 cr unu---uuuuu 170328e19920601xx s 000 0 eng 10.1007/BF01029665 doi (NATIONALLICENCE)springer-10.1007/BF01029665 Preparation and investigation of the tenoxicam/ β -cyclodextrin complex [Elektronische Daten] [Sevda Şenel, Önder Çakoĝlu, Murat Şumnu, Dominique Duchêne, A. Hincal] A complex of tenoxicam withβ-cyclodextrin was prepared by using co-grinding and freeze drying methods. The resulting products were studied by the solubility method, ultraviolet and infrared spectroscopy, differential scanning calorimetry and X-ray diffractometry. The dissolution behaviour of the products was also examined. The dissolution rate of the co-ground and freeze-dried products was faster than that of the pure drug and the physical mixture of drug andβ-cyclodextrin. The enhanced dissolution rate of the products might be attributed to the amorphous state, the increased wettability of the drug and the inclusion complex formation. Kluwer Academic Publishers, 1992 Tenoxicam/ β -cyclodextrin complexation nationallicence freeze-drying method nationallicence co-grinding method nationallicence characterization of inclusion complexes nationallicence Şenel Sevda Faculty of Pharmacy, Pharmaceutical Technology Department, Hacettepe University, 06100, Ankara, Türkiye aut Çakoĝlu Önder Faculty of Pharmacy, Pharmaceutical Technology Department, Hacettepe University, 06100, Ankara, Türkiye aut Şumnu Murat Faculty of Pharmacy, Pharmaceutical Technology Department, Hacettepe University, 06100, Ankara, Türkiye aut Duchêne Dominique Laboratorie de Pharmacie Galénique et de Biopharmacie, URA CNRS 1218, Université Paris Sud, 92296, Chatenay-Malabry, Cedex, France aut Hincal A. Faculty of Pharmacy, Pharmaceutical Technology Department, Hacettepe University, 06100, Ankara, Türkiye aut Journal of inclusion phenomena and molecular recognition in chemistry Kluwer Academic Publishers 14/2(1992-06-01), 171-179 0923-0750 14:2<171 1992 14 10847 https://doi.org/10.1007/BF01029665 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01029665 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Şenel Sevda Faculty of Pharmacy, Pharmaceutical Technology Department, Hacettepe University, 06100, Ankara, Türkiye aut NATIONALLICENCE 700 1- Çakoĝlu Önder Faculty of Pharmacy, Pharmaceutical Technology Department, Hacettepe University, 06100, Ankara, Türkiye aut NATIONALLICENCE 700 1- Şumnu Murat Faculty of Pharmacy, Pharmaceutical Technology Department, Hacettepe University, 06100, Ankara, Türkiye aut NATIONALLICENCE 700 1- Duchêne Dominique Laboratorie de Pharmacie Galénique et de Biopharmacie, URA CNRS 1218, Université Paris Sud, 92296, Chatenay-Malabry, Cedex, France aut NATIONALLICENCE 700 1- Hincal A. Faculty of Pharmacy, Pharmaceutical Technology Department, Hacettepe University, 06100, Ankara, Türkiye aut NATIONALLICENCE 773 0- Journal of inclusion phenomena and molecular recognition in chemistry Kluwer Academic Publishers 14/2(1992-06-01), 171-179 0923-0750 14:2<171 1992 14 10847 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer