caa a22 4500 469060484 CHVBK 20180323132855.0 cr unu---uuuuu 170328e19921101xx s 000 0 eng 10.1007/BF01201496 doi (NATIONALLICENCE)springer-10.1007/BF01201496 A review of recent immunochemical studies of Blomia tropicalis and Euroglyphus maynei allergens [Elektronische Daten] [L. Arruda, Martin Chapman] Exposure to mites other thanDermatophagoides spp., particularlyBlomia tropicalis andEuroglyphus maynei, has been increasingly recognized as a cause of asthma. Positive skin tests and serum IgE antibodies toB. tropicalis have been reported in asthmatic patients from several areas of the world, including São Paulo (Brazil), Hong Kong and Tampa (Florida, USA). Analysis ofB. tropicalis extracts showed undetectable levels of the major Group I and Group IIDermatophagoides spp. allergens. Immunoabsorption experiments showed that most of the IgE antibodies toB. tropicalis (∼ 70%) reacted with species-specific allergens. Murine monoclonal antibodies toB. tropicalis could present antigens that were recognized by human IgG antibodies. Sensitization toE. maynei has been reported in Europe, North and South America and Australia. Analysis of four differentE. maynei extracts by ELISA and RIA showed thatE. maynei produces an allergen that is antigenically related toDermatophagoides Group I allergens. The amino acid sequence of this allergen (Eur m I) has recently been reported. Further identification and purification ofB. tropicalis andE. maynei allergens is required to develop specific assays for measuring these allergens in dust samples. This will make it possible to investigate the relationship between exposure toB. tropicalis orE. maynei and the development of sensitization and allergic disease. Elsevier Science Publishers B.V., 1992 Arruda L. Division of Allergy and Clinical Immunology, Department of Medicine, University of Virginia, Box 225, 22908, Charlottesville, VA, USA aut Chapman Martin Division of Allergy and Clinical Immunology, Department of Medicine, University of Virginia, Box 225, 22908, Charlottesville, VA, USA aut Experimental & Applied Acarology Kluwer Academic Publishers 16/1-2(1992-11-01), 129-140 0168-8162 16:1-2<129 1992 16 10493 https://doi.org/10.1007/BF01201496 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01201496 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Arruda L. Division of Allergy and Clinical Immunology, Department of Medicine, University of Virginia, Box 225, 22908, Charlottesville, VA, USA aut NATIONALLICENCE 700 1- Chapman Martin Division of Allergy and Clinical Immunology, Department of Medicine, University of Virginia, Box 225, 22908, Charlottesville, VA, USA aut NATIONALLICENCE 773 0- Experimental & Applied Acarology Kluwer Academic Publishers 16/1-2(1992-11-01), 129-140 0168-8162 16:1-2<129 1992 16 10493 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer