caa a22 4500 469061464 CHVBK 20180323132858.0 cr unu---uuuuu 170328e19921201xx s 000 0 eng 10.1007/BF00355433 doi (NATIONALLICENCE)springer-10.1007/BF00355433 Mapping of recombinant retrovirus integration sites that cause expression of the viral genome in murine embryonal carcinoma cells [Elektronische Daten] [Makoto Taketo, Thad Howard, Michael Seldin] Murine embryonal carcinoma (EC) cells do not normally express Moloney murine leukemia virus genes. Earlier, rare EC cell lines were isolated that expressed proviral neomycin resistance (neo) gene. This expression was dependent on cellular enhancer or promoter sequences that flank the proviral integration site. Four such integration sites, designated as Mint (for Moloney murine leukemia virus integration and expression sites in EC cells), have been mapped on mouse chromosomes. Minta, Mintb, Mintc and Mintd are unlinked and mapped on different chromosomes (Chr), Chr 10, Chr 1, Chr 5 and the X Chr, respectively. None of these loci appear to be linded to any known Mo-MuLV proviral integration sites previously mapped. These enhancer and promoter loci may represent a new set of genes active in undifferentiated embryonic cells. Springer-Verlag New York Inc, 1992 Taketo Makoto Department of Microbiology and Immunology, Duke University Medical Center, 27710, Durham, North Carolina, USA aut Howard Thad Department of Medicine, Duke University Medical Center, 27710, Durham, North Carolina, USA aut Seldin Michael Department of Microbiology and Immunology, Duke University Medical Center, 27710, Durham, North Carolina, USA aut Mammalian Genome Springer-Verlag 2/4(1992-12-01), 240-245 0938-8990 2:4<240 1992 2 335 https://doi.org/10.1007/BF00355433 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00355433 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Taketo Makoto Department of Microbiology and Immunology, Duke University Medical Center, 27710, Durham, North Carolina, USA aut NATIONALLICENCE 700 1- Howard Thad Department of Medicine, Duke University Medical Center, 27710, Durham, North Carolina, USA aut NATIONALLICENCE 700 1- Seldin Michael Department of Microbiology and Immunology, Duke University Medical Center, 27710, Durham, North Carolina, USA aut NATIONALLICENCE 773 0- Mammalian Genome Springer-Verlag 2/4(1992-12-01), 240-245 0938-8990 2:4<240 1992 2 335 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer