caa a22 4500 469061693 CHVBK 20180323132859.0 cr unu---uuuuu 170328e19920101xx s 000 0 eng 10.1007/BF00355840 doi (NATIONALLICENCE)springer-10.1007/BF00355840 Localization of genes and anonymous DNA probes on the short arm of Chromosome 7 [Elektronische Daten] [Klaus Wagner, Peter Kroisel, Walter Rosenkranz] We have previously described the cytogenetic analysis of two patients with Greig cephalopolysyndactyly syndrome (GCPS) and various microdeletions on the short arm of Chromosome (Chr) 7. Using genes and anonymous DNA probes from 7p we analyzed the DNA of our patients for loss of heterozygosity, or we determined the copy number by semiquantitative Southern hybridization. We have been able to show hemizygosity for the genes of INHBA, IGFBP1 and GLI3 in both patients and therefore can give the chromosomal assignment 7p 12.3-p13. CRI-R944 and CRI-P137 map to the same region, whereas CRI-S207 can be assigned to 7p13-p14.2; TM102L, TS93, TS194, TM77 and TN177 showed no change and these probes map distal to 7p14.2. Springer-Verlag New York Inc, 1992 Wagner Klaus Institute of Medical Biology and Human Genetics, Harrachgasse 21/8, A-8010, Graz, Austria aut Kroisel Peter Institute of Medical Biology and Human Genetics, Harrachgasse 21/8, A-8010, Graz, Austria aut Rosenkranz Walter Institute of Medical Biology and Human Genetics, Harrachgasse 21/8, A-8010, Graz, Austria aut Mammalian Genome Springer-Verlag 3/1(1992-01-01), 39-41 0938-8990 3:1<39 1992 3 335 https://doi.org/10.1007/BF00355840 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00355840 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wagner Klaus Institute of Medical Biology and Human Genetics, Harrachgasse 21/8, A-8010, Graz, Austria aut NATIONALLICENCE 700 1- Kroisel Peter Institute of Medical Biology and Human Genetics, Harrachgasse 21/8, A-8010, Graz, Austria aut NATIONALLICENCE 700 1- Rosenkranz Walter Institute of Medical Biology and Human Genetics, Harrachgasse 21/8, A-8010, Graz, Austria aut NATIONALLICENCE 773 0- Mammalian Genome Springer-Verlag 3/1(1992-01-01), 39-41 0938-8990 3:1<39 1992 3 335 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer