caa a22 4500 469061820 CHVBK 20180323132859.0 cr unu---uuuuu 170328e19920301xx s 000 0 eng 10.1007/BF00352462 doi (NATIONALLICENCE)springer-10.1007/BF00352462 Completion of the physical map of Xq28: the location of the gene for L1CAM on the human X Chromosome [Elektronische Daten] [Alexander Dietrich, Bernhard Korn, Annemarie Poustka] The gene for the neural cell adhesion molecule L1 (L1CAM) has been shown to be located close to the color vision pigment genes in mouse and man. This location has been confirmed by a number of different mapping strategies in both species. With pulsed field gel electrophoresis it has been proposed that L1CAM lies between the RCP, GCP, and GDX, G6PD loci. We report here a reinterpretation of the location of this gene, based on the physical linkage of L1CAM to the more proximal locus DXS15. This places L1CAM between this marker and the color vision genes (RCP, GCP), a region very dense in CpG islands, expected to contain a large fraction of the disease genes assigned to the Xq28 region. In combination with the physical mapping data on Xq28 described previously, this closes the last remaining gap in the map of the Xq27-Xq28 region. This removes the last contradiction between the maps of this region in the genomes of man and mouse, and confirms the close similarity of order and distances of markers between these organisms. Springer-Verlag New York Inc, 1992 Dietrich Alexander Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 6900, Heidelberg, Germany aut Korn Bernhard Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 6900, Heidelberg, Germany aut Poustka Annemarie Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 6900, Heidelberg, Germany aut Mammalian Genome Springer-Verlag 3/3(1992-03-01), 168-172 0938-8990 3:3<168 1992 3 335 https://doi.org/10.1007/BF00352462 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00352462 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dietrich Alexander Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 6900, Heidelberg, Germany aut NATIONALLICENCE 700 1- Korn Bernhard Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 6900, Heidelberg, Germany aut NATIONALLICENCE 700 1- Poustka Annemarie Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 6900, Heidelberg, Germany aut NATIONALLICENCE 773 0- Mammalian Genome Springer-Verlag 3/3(1992-03-01), 168-172 0938-8990 3:3<168 1992 3 335 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer