caa a22 4500 469062541 CHVBK 20180323132901.0 cr unu---uuuuu 170328e19920501xx s 000 0 eng 10.1007/BF00292151 doi (NATIONALLICENCE)springer-10.1007/BF00292151 Comparative mapping of mouse Chromosome 4 and human Chromosome 9: Lv, Orm , and Hxb are closely linked on mouse Chromosome 4 [Elektronische Daten] [Alison Pilz, Heather Moseley, Jo Peters, Cathy Abbott] The genes for orosomucoid (ORM-1 and ORM-2), delta-aminolevulinate dehydratase (ALAD), and hexabrachion or tenascin (HXB) all map to the q31-qter region of human Chromosome (Chr) 9. The mouse homolog of each of these genes has been mapped to Chr 4, but hexabrachion has not previously been mapped by linkage analysis. We have now ordered Orm-1, Lv (the mouse homolog of ALAD), and Hxb in an interspecific backcross panel, by use of tyrosinase related protein-1, Tyrp-1, whose human homolog maps to 9p13-pter (Abbott et al., Genomics 1991) as a reference locus. No recombinants were identified in 124 animals between Lv and Orm-1. Hxb was found to be 1.6 cM distal to Lv and Orm-1, and 4.8 cM proximal to Tyrp-1, or b. These data therefore contribute to our knowledge of the conserved synteny between HSA 9q and MMU 4. Springer-Verlag New York Inc, 1992 Pilz Alison Department of Genetics & Biometry, University College London, Wolfson House, 4 Stephenson Way, NW1 2HE, London, UK aut Moseley Heather MRC Radiobiology Unit, Chilton, OX11 ORD, Didcot, Oxon, UK aut Peters Jo MRC Radiobiology Unit, Chilton, OX11 ORD, Didcot, Oxon, UK aut Abbott Cathy Department of Genetics & Biometry, University College London, Wolfson House, 4 Stephenson Way, NW1 2HE, London, UK aut Mammalian Genome Springer-Verlag 3/5(1992-05-01), 247-249 0938-8990 3:5<247 1992 3 335 https://doi.org/10.1007/BF00292151 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00292151 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pilz Alison Department of Genetics & Biometry, University College London, Wolfson House, 4 Stephenson Way, NW1 2HE, London, UK aut NATIONALLICENCE 700 1- Moseley Heather MRC Radiobiology Unit, Chilton, OX11 ORD, Didcot, Oxon, UK aut NATIONALLICENCE 700 1- Peters Jo MRC Radiobiology Unit, Chilton, OX11 ORD, Didcot, Oxon, UK aut NATIONALLICENCE 700 1- Abbott Cathy Department of Genetics & Biometry, University College London, Wolfson House, 4 Stephenson Way, NW1 2HE, London, UK aut NATIONALLICENCE 773 0- Mammalian Genome Springer-Verlag 3/5(1992-05-01), 247-249 0938-8990 3:5<247 1992 3 335 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer