caa a22 4500 469062614 CHVBK 20180323132902.0 cr unu---uuuuu 170328e19920201xx s 000 0 eng 10.1007/BF00431249 doi (NATIONALLICENCE)springer-10.1007/BF00431249 Random sequence oligonucleotide primers detect polymorphic DNA products which segregate in inbred strains of mice [Elektronische Daten] [Scott Woodward, Jayce Sudweeks, Cory Teuscher] The random amplification of polymorphic DNA (RAPD) using primers of arbitrary nucleotide sequence has been extremely valuable in identifying heritable markers in a variety of systems. The present studies examined whether the RAPD technique can identify large numbers of polymorphisms that can be used to construct genetic maps in inbred strains of mice. By screening the inbred mouse strains C57BL/6J and DBA/2J with 481 random 10-mer oligonucleotide primers, we identified 95 polymorphisms and mapped 76 of these by use of the BXD series of recombinant inbred (RI) strains. The results clearly demonstrate that the RAPD technique allows for the identification of large numbers of DNA-based polymorphisms that distinguish these two inbred strains of mice,and that such markers can readily be used to construct molecular genetic linkage maps. Springer-Verlag New York Inc, 1992 Woodward Scott Department of Microbiology, 873 WIDB, Brigham Young University, 84602, Provo, Utah, USA aut Sudweeks Jayce Department of Microbiology, 873 WIDB, Brigham Young University, 84602, Provo, Utah, USA aut Teuscher Cory Department of Microbiology, 873 WIDB, Brigham Young University, 84602, Provo, Utah, USA aut Mammalian Genome Springer-Verlag 3/2(1992-02-01), 73-78 0938-8990 3:2<73 1992 3 335 https://doi.org/10.1007/BF00431249 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00431249 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Woodward Scott Department of Microbiology, 873 WIDB, Brigham Young University, 84602, Provo, Utah, USA aut NATIONALLICENCE 700 1- Sudweeks Jayce Department of Microbiology, 873 WIDB, Brigham Young University, 84602, Provo, Utah, USA aut NATIONALLICENCE 700 1- Teuscher Cory Department of Microbiology, 873 WIDB, Brigham Young University, 84602, Provo, Utah, USA aut NATIONALLICENCE 773 0- Mammalian Genome Springer-Verlag 3/2(1992-02-01), 73-78 0938-8990 3:2<73 1992 3 335 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer