caa a22 4500 469062746 CHVBK 20180323132902.0 cr unu---uuuuu 170328e19921101xx s 000 0 eng 10.1007/BF00352480 doi (NATIONALLICENCE)springer-10.1007/BF00352480 Mapping of the structural gene for S-adenosyl homocysteine hydrolase to mouse Chromosome 2, and related sequences to Chromosomes 8 and X [Elektronische Daten] [Alison Pilz, Paul Le Tissier, Heather Moseley, Jo Peters, Cathy Abbott] Comparative mapping studies in human and mouse have shown that, to date, human Chromosome (Chr) 20 is completely syntenic with distal mouse Chr 2. The structural locus for S-adenosyl-l-homocysteine hydrolase (EC 3.3.1.1) in human, AHCY, maps to 20 qter→q13.1, and we report here that the homologous locus in the mouse, Ahcy, maps to distal mouse Chr 2 with gene order Pcna-Ahcy-Ada. Analysis of 123 progeny of an interspecific backcross between a laboratory stock, AN, and Mus spretus using a rat cDNA probe revealed the presence of at least two other Ahcy-related sequences segregating independently in the mouse genome. One, Ahcy-rs1, was mapped to Chr 8 in the BXH recombinant inbred strains, and the other, Ahcy-rs2, shows a pattern of inheritance consistent with X-linkage. Springer-Verlag New York Inc, 1992 Pilz Alison Department of Genetics and Biometry, University College London, Wolfson House, 4 Stephenson Way, NW1 2HE, London, UK aut Le Tissier Paul MRC Radiobiology Unit, Chilton, OX11 ORD, Didcot, Oxon, UK aut Moseley Heather MRC Radiobiology Unit, Chilton, OX11 ORD, Didcot, Oxon, UK aut Peters Jo MRC Radiobiology Unit, Chilton, OX11 ORD, Didcot, Oxon, UK aut Abbott Cathy Department of Genetics and Biometry, University College London, Wolfson House, 4 Stephenson Way, NW1 2HE, London, UK aut Mammalian Genome Springer-Verlag 3/11(1992-11-01), 633-636 0938-8990 3:11<633 1992 3 335 https://doi.org/10.1007/BF00352480 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00352480 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pilz Alison Department of Genetics and Biometry, University College London, Wolfson House, 4 Stephenson Way, NW1 2HE, London, UK aut NATIONALLICENCE 700 1- Le Tissier Paul MRC Radiobiology Unit, Chilton, OX11 ORD, Didcot, Oxon, UK aut NATIONALLICENCE 700 1- Moseley Heather MRC Radiobiology Unit, Chilton, OX11 ORD, Didcot, Oxon, UK aut NATIONALLICENCE 700 1- Peters Jo MRC Radiobiology Unit, Chilton, OX11 ORD, Didcot, Oxon, UK aut NATIONALLICENCE 700 1- Abbott Cathy Department of Genetics and Biometry, University College London, Wolfson House, 4 Stephenson Way, NW1 2HE, London, UK aut NATIONALLICENCE 773 0- Mammalian Genome Springer-Verlag 3/11(1992-11-01), 633-636 0938-8990 3:11<633 1992 3 335 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer