caa a22 4500 469063998 CHVBK 20180323132902.0 cr unu---uuuuu 170328e19920301xx s 000 0 eng 10.1007/BF02914371 doi (NATIONALLICENCE)springer-10.1007/BF02914371 IVIG therapy in neonatal isoimmune thrombocytopenic purpura and alloimmunization thrombocytopenia [Elektronische Daten] [Joanne Kurtzherg, Kimberly Dunsmore] IVIG is a valuable therapeutic intervention in a broad spectrum of disorders, including the treatment of the alloimmunized patient. IVIG appears to be well tolerated in the pregnant woman and the fetus. Although potential risks associated with IVIG therapy include transmission of infectious agents and allergic reactions, the vast clinical experience to date suggests that these are infrequent complications. The high cost of therapy remains a potential draw-back. Current data support the continued use of IVIG in the antenatal and postnatal treatment of isoimmune neonatal thrombocytopenia. IVIG may be useful in the treatment of platelet alloimmunization in the platelet-transfusion-dependent patient with one marrow failure and clinical hemorrhage, but in this situation responses to IVIG are varied, often transient, and methods to predict efficacy are not currently available. The Humana Press Inc, 1992 Kurtzherg Joanne Department of Pediatrics, Division of Hematology and Oncology, Duke University Medical Center, 27710, Durham, NC aut Dunsmore Kimberly Department of Pediatrics, Division of Hematology and Oncology, Duke University Medical Center, 27710, Durham, NC aut Clinical Reviews in Allergy Humana Press 10/1-2(1992-03-01), 73-80 0731-8235 10:1-2<73 1992 10 12016 https://doi.org/10.1007/BF02914371 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02914371 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kurtzherg Joanne Department of Pediatrics, Division of Hematology and Oncology, Duke University Medical Center, 27710, Durham, NC aut NATIONALLICENCE 700 1- Dunsmore Kimberly Department of Pediatrics, Division of Hematology and Oncology, Duke University Medical Center, 27710, Durham, NC aut NATIONALLICENCE 773 0- Clinical Reviews in Allergy Humana Press 10/1-2(1992-03-01), 73-80 0731-8235 10:1-2<73 1992 10 12016 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer