caa a22 4500 469072156 CHVBK 20180323132924.0 cr unu---uuuuu 170328e19920601xx s 000 0 eng 10.1007/BF00678417 doi (NATIONALLICENCE)springer-10.1007/BF00678417 Conformational studies of haloperidol [Elektronische Daten] [Charles Keller, Paul Karr, Melvin Zandler, W. Carper] The high field1H,19F, and13C NMR spectra of haloperidol (HP) in CDCl3 solution were recorded and analyzed with the aid of both homonuclear (H, H-COSY, H, H-COSYLR) and heteronuclear (H,C-COSY) chemical shift correlation experiments. Through space interactions between (1) the piperidine ring and the chlorinated phenyl ring and (2) the fluorinated phenyl ring and a methylene group were identified using phase sensitive Nuclear Overhauser and Exchange Spectroscopy (NOESY). The NOESY results are consistent with a planar structure rather than a folded version of haloperidol. Plenum Publishing Corporation, 1992 Keller Charles Department of Chemistry, Wichita State University, 67208, Wichita, Kansas, USA aut Karr Paul Department of Chemistry, Wichita State University, 67208, Wichita, Kansas, USA aut Zandler Melvin Department of Chemistry, Wichita State University, 67208, Wichita, Kansas, USA aut Carper W. Department of Chemistry, Wichita State University, 67208, Wichita, Kansas, USA aut Structural Chemistry Kluwer Academic Publishers 3/3(1992-06-01), 195-201 1040-0400 3:3<195 1992 3 11224 https://doi.org/10.1007/BF00678417 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00678417 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Keller Charles Department of Chemistry, Wichita State University, 67208, Wichita, Kansas, USA aut NATIONALLICENCE 700 1- Karr Paul Department of Chemistry, Wichita State University, 67208, Wichita, Kansas, USA aut NATIONALLICENCE 700 1- Zandler Melvin Department of Chemistry, Wichita State University, 67208, Wichita, Kansas, USA aut NATIONALLICENCE 700 1- Carper W. Department of Chemistry, Wichita State University, 67208, Wichita, Kansas, USA aut NATIONALLICENCE 773 0- Structural Chemistry Kluwer Academic Publishers 3/3(1992-06-01), 195-201 1040-0400 3:3<195 1992 3 11224 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer