caa a22 4500 469076062 CHVBK 20180323132935.0 cr unu---uuuuu 170328e19921201xx s 000 0 eng 10.1007/BF02927890 doi (NATIONALLICENCE)springer-10.1007/BF02927890 Statistical analysis of family data on complex disorders in man [Elektronische Daten] [Partha Majumder, Swapan Nath] A genetic model is discussed for recessively inherited disorders that do not follow a single-locus Mendelian pattern of inheritance. Further complexity arising from variable age of onset is also discussed. Methods of statistical analysis of family data using the likelihood principle are described for such complex disorders. The methods are exemplified using data on families of prelingual deafness and vitiligo. Indian Academy of Sciences, 1992 Segregation analysis nationallicence autosomal recessive nationallicence multiple loci nationallicence variable onset age nationallicence prelingual deafness nationallicence vitiligo nationallicence Majumder Partha Anthropometry & Human Genetics Unit, Indian Statistical Institute, 700 035, Calcutta, India aut Nath Swapan Anthropometry & Human Genetics Unit, Indian Statistical Institute, 700 035, Calcutta, India aut Journal of Genetics Springer India 71/3(1992-12-01), 89-103 0022-1333 71:3<89 1992 71 12041 https://doi.org/10.1007/BF02927890 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02927890 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Majumder Partha Anthropometry & Human Genetics Unit, Indian Statistical Institute, 700 035, Calcutta, India aut NATIONALLICENCE 700 1- Nath Swapan Anthropometry & Human Genetics Unit, Indian Statistical Institute, 700 035, Calcutta, India aut NATIONALLICENCE 773 0- Journal of Genetics Springer India 71/3(1992-12-01), 89-103 0022-1333 71:3<89 1992 71 12041 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer