caa a22 4500 469078383 CHVBK 20180323132942.0 cr unu---uuuuu 170328e19921001xx s 000 0 eng 10.1007/BF00171093 doi (NATIONALLICENCE)springer-10.1007/BF00171093 Depression by neuropeptide Y of noradrenergic inhibitory postsynaptic potentials of locus coeruleus neurones [Elektronische Daten] [Ervin Finta, Jürgen Regenold, Peter Illes] Summary: Intracellular recordings were performed in a pontine slice preparation of the rat brain containing the locus coeruleus (LC). The spontaneous firing of action potentials was prevented by passing continuous hyperpolarizing current via the recording electrode. Focal electrical stimulation evoked a synaptic depolarization (PSP) followed by a hyperpolarization (IPSP). Neuropeptide Y (NPY; 0.1 μmol/l) inhibited the IPSP only. Pressure ejection of noradrenaline produced hyperpolarization which was potentiated in the presence of NPY (0.1 μmol/l). Hence, NPY appears to inhibit the release of noradrenaline from dendrites or recurrent axon collaterals of LC neurones. Springer-Verlag, 1992 Neuropeptide Y nationallicence Locus coeruleus nationallicence Noradrenaline release nationallicence Presynaptic inhibition nationallicence Postsynaptic potentiation nationallicence Finta Ervin Department of Pharmacology, University of Freiburg, Hermann-Herder-Strasse 5, W-7800, Freiburg, Federal Republic of Germany aut Regenold Jürgen Department of Pharmacology, University of Freiburg, Hermann-Herder-Strasse 5, W-7800, Freiburg, Federal Republic of Germany aut Illes Peter Department of Pharmacology, University of Freiburg, Hermann-Herder-Strasse 5, W-7800, Freiburg, Federal Republic of Germany aut Naunyn-Schmiedeberg's Archives of Pharmacology Springer-Verlag 346/4(1992-10-01), 472-474 0028-1298 346:4<472 1992 346 210 https://doi.org/10.1007/BF00171093 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00171093 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Finta Ervin Department of Pharmacology, University of Freiburg, Hermann-Herder-Strasse 5, W-7800, Freiburg, Federal Republic of Germany aut NATIONALLICENCE 700 1- Regenold Jürgen Department of Pharmacology, University of Freiburg, Hermann-Herder-Strasse 5, W-7800, Freiburg, Federal Republic of Germany aut NATIONALLICENCE 700 1- Illes Peter Department of Pharmacology, University of Freiburg, Hermann-Herder-Strasse 5, W-7800, Freiburg, Federal Republic of Germany aut NATIONALLICENCE 773 0- Naunyn-Schmiedeberg's Archives of Pharmacology Springer-Verlag 346/4(1992-10-01), 472-474 0028-1298 346:4<472 1992 346 210 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer