caa a22 4500 469082003 CHVBK 20180323132953.0 cr unu---uuuuu 170328e19920601xx s 000 0 eng 10.1007/BF00319150 doi (NATIONALLICENCE)springer-10.1007/BF00319150 Evaluation of mRNA steady-state and protein levels for basement membrane proteins in cultured murine cells [Elektronische Daten] [Ilse Oberbäumer, Cornelia Speth] Summary: We have determined the mRNA steady-state levels for the six constituent polypeptide chains of the basement membrane proteins collagen IV, laminin and nidogen in murine cell lines derived from a teratocarcinoma, and in some other cell lines of different origin in stationary cultures and during different growth phases. The mRNA and protein levels change in response to growth phase. The amounts of the mRNAs for the single chains do not agree with the ratios needed for the different peptide chains of collagen IV and laminin. While the mRNA and protein levels for laminin are in a similar range for the teratocarcinoma-derived cell lines, the mRNA and protein levels vary by at least a factor of 10 for collagen IV. These results point to complex posttranscriptional regulatory mechanisms for the biosynthesis of basement membrane proteins. Springer-Verlag, 1992 Collagen IV nationallicence Laminin nationallicence Nidogen nationallicence Teratocarcinoma nationallicence Tissue culture conditions nationallicence Post-transcriptional control nationallicence mRNA quantification nationallicence Murine cell lines nationallicence Oberbäumer Ilse Max-Planck-Institut für Biochemie, W-8033, Martinsried, Germany aut Speth Cornelia Max-Planck-Institut für Biochemie, W-8033, Martinsried, Germany aut Cell and Tissue Research Springer-Verlag 268/3(1992-06-01), 439-445 0302-766X 268:3<439 1992 268 441 https://doi.org/10.1007/BF00319150 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00319150 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Oberbäumer Ilse Max-Planck-Institut für Biochemie, W-8033, Martinsried, Germany aut NATIONALLICENCE 700 1- Speth Cornelia Max-Planck-Institut für Biochemie, W-8033, Martinsried, Germany aut NATIONALLICENCE 773 0- Cell and Tissue Research Springer-Verlag 268/3(1992-06-01), 439-445 0302-766X 268:3<439 1992 268 441 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer