caa a22 4500 469082062 CHVBK 20180323132953.0 cr unu---uuuuu 170328e19920501xx s 000 0 eng 10.1007/BF00318809 doi (NATIONALLICENCE)springer-10.1007/BF00318809 Expression of atrial natriuretic peptide in thymic macrophages after dexamethasone treatment of rats [Elektronische Daten] [Angelika Vollmar, Florian Colbatzky, Rüdiger Schulz] Summary: The rat thymus represents a site of synthesis of atrial natriuretic peptide (ANP); the immunosuppressor dexamethasone strikingly increases ANP-expression in this immune organ. The presented data suggest that this increase can be attributed to macrophages. By means of immunohistochemistry and Northern blot analysis these immune cells were found to express ANP-immunoreactivity as well as mRNA coding for ANP. In contrast, macrophages of control thymi displayed only weak ANP-immunoreactivity. Thus, ANP appears to be a constituent of rat thymic macrophages, and its synthesis in the thymus is strongly elevated by acute exposure of the animals to glucocorticoids. Springer-Verlag, 1992 Atrial natriuretic peptide (ANP) nationallicence Macrophages nationallicence Thymus nationallicence Dexamethasone nationallicence Rat (Sprague-Dawley) nationallicence Vollmar Angelika Institut für Pharmakologie, Toxikologie und Pharmazie, Universität München, Königinstrasse 16, W-8000, München 22, Germany aut Colbatzky Florian Institut für Veterinärpathologie der Universität, Veterinärstrasse 13, W-8000, München 22, Germany aut Schulz Rüdiger Institut für Pharmakologie, Toxikologie und Pharmazie, Universität München, Königinstrasse 16, W-8000, München 22, Germany aut Cell and Tissue Research Springer-Verlag 268/2(1992-05-01), 397-399 0302-766X 268:2<397 1992 268 441 https://doi.org/10.1007/BF00318809 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00318809 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Vollmar Angelika Institut für Pharmakologie, Toxikologie und Pharmazie, Universität München, Königinstrasse 16, W-8000, München 22, Germany aut NATIONALLICENCE 700 1- Colbatzky Florian Institut für Veterinärpathologie der Universität, Veterinärstrasse 13, W-8000, München 22, Germany aut NATIONALLICENCE 700 1- Schulz Rüdiger Institut für Pharmakologie, Toxikologie und Pharmazie, Universität München, Königinstrasse 16, W-8000, München 22, Germany aut NATIONALLICENCE 773 0- Cell and Tissue Research Springer-Verlag 268/2(1992-05-01), 397-399 0302-766X 268:2<397 1992 268 441 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer