caa a22 4500 469082178 CHVBK 20180323132953.0 cr unu---uuuuu 170328e19920501xx s 000 0 eng 10.1007/BF00318807 doi (NATIONALLICENCE)springer-10.1007/BF00318807 Transient serotonin-immunoreactive neurons coincide with a critical period of neural development in coho salmon ( Oncorhynchus kisutch ) [Elektronische Daten] [Lars Ebbesson, Bo Holmqvist, Thomas Östholm, Peter Ekström] Summary: In coho salmon (Oncorhynchus kisutch), smolt transformation has been shown to be associated with sequential surges of neurotransmitters in the brain. In order to determine if the surge of serotonin (5-HT) is correlated with structural changes, we have used immunocytochemistry to observe changes in the serotonin immunoreactivity before, during and after the 5-HT surge. The following stages were studied: 12-month-old freshwater presmolts, 17-month-old freshwater presmolts, 18-month-old saltwater smolts, 19-month-old saltwater postsmolt, 24-month-old postsmolt, and adult spawners. In the 17-month-old samples, but not at any other stage, we found a set of transient (serotonin-immunoreactive) 5-HT-immunoreactive neurons in the lateral preoptic area, as well as a discrete population of 5-HT-immunoreactive neurons in the lateral part of the dorsal right habenular nucleus. In addition, a higher density of serotonergic fibers was found in the telencephalon at this stage compared to the following two stages. Since the transient 5-HT-immunoreactive structures presented here do not appear simultaneously with the 5-HT total brain concentration surge, we conclude that they are unlikely to be the source of the 5-HT surge, but are probably related to other developmental changes in the brain associated with smolt transformation. Springer-Verlag, 1992 Neural development nationallicence Plasticity nationallicence Serotonin nationallicence Immunohistochemistry nationallicence Coho salmon, Oncorhynchus kisutch (Teleostei) nationallicence Ebbesson Lars Institute of Marine Science and Department of Chemistry, University of Alaska, 99775-1080, Fairbanks, AK, USA aut Holmqvist Bo Laboratory of Molecular Neuroanatomy, Department of Zoology, University of Lund, Helgonavägen 3, S-22362, Lund, Sweden aut Östholm Thomas Institute of Marine Science and Department of Chemistry, University of Alaska, 99775-1080, Fairbanks, AK, USA aut Ekström Peter Laboratory of Molecular Neuroanatomy, Department of Zoology, University of Lund, Helgonavägen 3, S-22362, Lund, Sweden aut Cell and Tissue Research Springer-Verlag 268/2(1992-05-01), 389-392 0302-766X 268:2<389 1992 268 441 https://doi.org/10.1007/BF00318807 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00318807 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ebbesson Lars Institute of Marine Science and Department of Chemistry, University of Alaska, 99775-1080, Fairbanks, AK, USA aut NATIONALLICENCE 700 1- Holmqvist Bo Laboratory of Molecular Neuroanatomy, Department of Zoology, University of Lund, Helgonavägen 3, S-22362, Lund, Sweden aut NATIONALLICENCE 700 1- Östholm Thomas Institute of Marine Science and Department of Chemistry, University of Alaska, 99775-1080, Fairbanks, AK, USA aut NATIONALLICENCE 700 1- Ekström Peter Laboratory of Molecular Neuroanatomy, Department of Zoology, University of Lund, Helgonavägen 3, S-22362, Lund, Sweden aut NATIONALLICENCE 773 0- Cell and Tissue Research Springer-Verlag 268/2(1992-05-01), 389-392 0302-766X 268:2<389 1992 268 441 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer