caa a22 4500 469082402 CHVBK 20180323132954.0 cr unu---uuuuu 170328e19920101xx s 000 0 eng 10.1007/BF00318701 doi (NATIONALLICENCE)springer-10.1007/BF00318701 Aminergic neurons in the brain of blowflies and Drosophila: dopamine- and tyrosine hydroxylase-immunoreactive neurons and their relationship with putative histaminergic neurons [Elektronische Daten] [D. Nässel, K. Elekes] Summary: The distribution and morphology of neurons reacting with antisera against dopamine (DA), tyrosine hydroxylase (TH) and histamine (HA) were analyzed in the blowflies Calliphora erythrocephala and Phormia terraenovae. TH-immunoreactive (THIR) and HA-immunoreactive (HAIR) neurons were also mapped in the fruitfly Drosophila melanogaster. The antisera against DA and TH specifically labeled the same neurons in the blowflies. About 300 neurons displayed DA immunoreactivity (DAIR) and THIR in the brain and subesophageal ganglion of the blowflies. Most of these neurons were located in bilateral clusters; some were distributed as bilateral pairs, and two ventral unpaired median (VUM) neurons were seen in the subesophageal ganglion. Immunoreactive processes were found in all compartments of the mushroom bodies except the calyces, in all divisions of the central body complex, in the medulla, lobula and lobula plate of the optic lobe, and in non-glomerular neuropil of protocerebrum, tritocerebrum and the subesophageal ganglion. No DA or TH immunoreactivity was seen in the antennal lobes. In Drosophila, neurons homologous to the blowfly neurons were detected with the TH antiserum. In Phormia and Drosophila, 18 HA-immunoreactive neurons were located in the protocerebrum and 2 in the subesophageal ganglion. The HAIR neurons arborized extensively, but except for processes in the lobula, all HAIR processes were seen in non-glomerular neuropil. The deuto- and tritocerebrum was devoid of HAIR processes. Double labeling experiments demonstrated that TH and HA immunoreactivity was not colocalized in any neuron. In some regions there wasm however, substantial superposition between the two systems. The morphology of the extensively arborizing aminergic neurons described suggests that they have modulatory functions in the brain and subesophageal ganglion. Springer-Verlag, 1992 Dopamine nationallicence Tyrosine hydroxylase nationallicence Histamine nationallicence Immunocytochemistry nationallicence Insect nervous system nationallicence Drosophila melanogaster, Phormia terraenovae, Calliphora erythrocephala (Insecta) nationallicence Nässel D. Department of Zoology, Stockholm University, S-10691, Stockholm, Sweden aut Elekes K. Balaton Limnological Research Institute of the Hungarian Academy of Sciences, Tihany, Hungary aut Cell and Tissue Research Springer-Verlag 267/1(1992-01-01), 147-167 0302-766X 267:1<147 1992 267 441 https://doi.org/10.1007/BF00318701 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00318701 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nässel D. Department of Zoology, Stockholm University, S-10691, Stockholm, Sweden aut NATIONALLICENCE 700 1- Elekes K. Balaton Limnological Research Institute of the Hungarian Academy of Sciences, Tihany, Hungary aut NATIONALLICENCE 773 0- Cell and Tissue Research Springer-Verlag 267/1(1992-01-01), 147-167 0302-766X 267:1<147 1992 267 441 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer