caa a22 4500 469082623 CHVBK 20180323132955.0 cr unu---uuuuu 170328e19920301xx s 000 0 eng 10.1007/BF00319374 doi (NATIONALLICENCE)springer-10.1007/BF00319374 Three-dimensional and quantitative observation of the hypertrophy of rat corticotrophs following adrenalectomy [Elektronische Daten] [Yutaka Taniguchi, Masataka Shiino] Summary: The three-dimensional form of corticotrophs in the anterior pitiutary gland of rats was studied by reconstruction from serial semi-thin sections both in control rats and rats one week after adrenalectomy. The corticotrophs have large depressions and cup-shaped cavities on their surface, and these features became more conspicuous after adrenalectomy. The hypertrophy of corticotrophs in adrenalectomized rats was quantified by measuring the area and perimeter of all serially sectioned profiles. The volume of the whole cell increased from 1129±114 μm3 to 2902±201 μm3 (P<0.01) after adrenalectomy, while the surface area of the cells increased from 690±45 μm2 to 1431±116 μm2 (P<0.01). The volume of the nucleus increased from 87±11 μm3 to 172±14 μm3 (P<0.05). Though the complexity of the form of corticotrophs seems to be increased after adrenalectomy, the ratios (adrenalectomized/control) of cell volume and surface area were 2.57 and 2.07, respectively; this indicates that the increase of the cell volume was greater than that of the surface area. Springer-Verlag, 1992 Pituitary gland, pars anterior nationallicence Corticotropes nationallicence Adrenalectomy nationallicence Reconstruction, 3D nationallicence Rat (Sprague-Dawley) nationallicence Taniguchi Yutaka Department of Anatomy, Wakayama Medical College, 27-Kyubancho, 640, Wakayama, Japan aut Shiino Masataka Department of Anatomy, Wakayama Medical College, 27-Kyubancho, 640, Wakayama, Japan aut Cell and Tissue Research Springer-Verlag 267/3(1992-03-01), 519-523 0302-766X 267:3<519 1992 267 441 https://doi.org/10.1007/BF00319374 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00319374 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Taniguchi Yutaka Department of Anatomy, Wakayama Medical College, 27-Kyubancho, 640, Wakayama, Japan aut NATIONALLICENCE 700 1- Shiino Masataka Department of Anatomy, Wakayama Medical College, 27-Kyubancho, 640, Wakayama, Japan aut NATIONALLICENCE 773 0- Cell and Tissue Research Springer-Verlag 267/3(1992-03-01), 519-523 0302-766X 267:3<519 1992 267 441 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer