caa a22 4500 469083093 CHVBK 20180323132956.0 cr unu---uuuuu 170328e19921001xx s 000 0 eng 10.1007/BF00381889 doi (NATIONALLICENCE)springer-10.1007/BF00381889 Herbert Horst Tierphysiologie, Universität Tübingen, Auf der Morgenstelle 28, W-7400, Tübingen, Federal Republic of Germany aut Evidence for projections from medullary nuclei onto serotonergic and dopaminergic neurons in the midbrain dorsal raphe nucleus of the rat [Elektronische Daten] [Horst Herbert] Summary: The anterograde tracer Phaseolus vulgaris-leucoagglutinin was injected into the medial nucleus of the solitary tract and into the rostral dorsomedial medulla. A sequential two-color immunoperoxidase staining was accomplished in order to demonstrate the co-distribution of presumed terminal axons with chemically distinct neurons in the dorsal raphe nucleus of the midbrain central gray, i.e., B7 serotonergic and A10dc dopaminergic neurons. Black-stained efferent fibers from the medial nucleus of the solitary tract and the rostral dorsomedial medulla intermingled with brown-stained serotonergic (5-hydroxytryptamine-immunoreactive) or dopaminergic (tyrosine hydroxylase-immunoreactive) neurons. Light microscopy revealed that the black-stained efferent axons exhibited numerous en passant and terminal varicosities that were often found in close apposition to brown-stained serotonergic and dopaminergic somata, and to proximal and distal dendrites and dendritic processes. The close association of immunoreactive elements suggests the presence of axo-somatic and axodendritic synaptic contacts of medullary fibers with serotonergic and dopaminergic neurons in the dorsal raphe nucleus. These projections could be involved in the modulation of dorsal raphe neurons, depending on the autonomic status of an animal. Springer-Verlag, 1992 Nucleus tractus solitarii nationallicence Dorsomedial medulla nationallicence Midbrain central gray nationallicence Autonomic control nationallicence 5-Hydroxytryptamine nationallicence Tyrosine hydroxylase nationallicence Central gray, mesencephalic, periaqueductal nationallicence Rat (Sprague-Dawley) nationallicence Cell and Tissue Research Springer-Verlag 270/1(1992-10-01), 149-156 0302-766X 270:1<149 1992 270 441 https://doi.org/10.1007/BF00381889 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00381889 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Herbert Horst Tierphysiologie, Universität Tübingen, Auf der Morgenstelle 28, W-7400, Tübingen, Federal Republic of Germany aut NATIONALLICENCE 773 0- Cell and Tissue Research Springer-Verlag 270/1(1992-10-01), 149-156 0302-766X 270:1<149 1992 270 441 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer