caa a22 4500 469083417 CHVBK 20180323132957.0 cr unu---uuuuu 170328e19921101xx s 000 0 eng 10.1007/BF00328009 doi (NATIONALLICENCE)springer-10.1007/BF00328009 Distribution of laminin, type IV collagen, and fibronectin in the cell columns and trophoblastic shell of early macaque placentas [Elektronische Daten] [Thomas Blankenship, Allen Enders, Barry King] Summary: The cytotrophoblastic cell columns and trophoblastic shell of macaque placentas accumulate progressively greater amounts of intercellular material during early gestation. We studied the composition of this material in placentas collected from 22-34 days of gestation by using immunoperoxidase techniques directed to the extracellular matrix molecules fibronectin, type IV collagen, and laminin. These antigens co-localized within the intercellular deposits at all stages studied. At day 22 the proximal cell columns were composed of cells with narrow interstices and which lacked immunoreactivity for the 3 antigens. Distally the cells were vacuolated and the intercellular spaces increased in size and contained dense matrix deposits. The trophoblastic shell consisted of closely packed, non-vacuolated cytotrophoblast cells with only a delicate meshwork of matrix. By day 27 the matrix deposits of the distal cell columns increased markedly in size. The trophoblastic shell contained larger numbers of vacuolated cells and was occupied by accumulations of matrix. By 34 days the matrix deposits of the cell columns expanded substantially along the longitudinal axes of the columns. These deposits were often continuous with a matrix-dense, cell-deficient layer in the trophoblastic shell. This matrix-rich zone lay between a cellular layer adjacent to the intervilous space and a similar, but discontinuous, cell layer that formed the junctional zone with the endometrium. Springer-Verlag, 1992 Trophoblast nationallicence Placenta nationallicence Laminin nationallicence Collagen nationallicence Fibronectin nationallicence Extracellular matrix,-structures nationallicence Macaca fascicularis (Primates) nationallicence Blankenship Thomas Department of Cell Biology and Human Anatomy, School of Medicine, University of California, Davis, 95616, Davis, CA, USA aut Enders Allen Department of Cell Biology and Human Anatomy, School of Medicine, University of California, Davis, 95616, Davis, CA, USA aut King Barry Department of Cell Biology and Human Anatomy, School of Medicine, University of California, Davis, 95616, Davis, CA, USA aut Cell and Tissue Research Springer-Verlag 270/2(1992-11-01), 241-248 0302-766X 270:2<241 1992 270 441 https://doi.org/10.1007/BF00328009 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00328009 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Blankenship Thomas Department of Cell Biology and Human Anatomy, School of Medicine, University of California, Davis, 95616, Davis, CA, USA aut NATIONALLICENCE 700 1- Enders Allen Department of Cell Biology and Human Anatomy, School of Medicine, University of California, Davis, 95616, Davis, CA, USA aut NATIONALLICENCE 700 1- King Barry Department of Cell Biology and Human Anatomy, School of Medicine, University of California, Davis, 95616, Davis, CA, USA aut NATIONALLICENCE 773 0- Cell and Tissue Research Springer-Verlag 270/2(1992-11-01), 241-248 0302-766X 270:2<241 1992 270 441 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer