caa a22 4500 469083808 CHVBK 20180323132958.0 cr unu---uuuuu 170328e19920901xx s 000 0 eng 10.1007/BF00353897 doi (NATIONALLICENCE)springer-10.1007/BF00353897 Immunohistochemical localization and radioenzymatic measurements of serotonin (5-hydroxytryptamine) in hearts of Aplysia and several bivalve mollusks [Elektronische Daten] [Joyce Ono, Jubal Hampton, Robert Koch] Summary: Serotonin immunoreactivity was localized in hearts of the opisthobranch gastropod, Aplysia californica (sca hare) and several species of bivalve mollusks, the heterodonts, Mercenaria mercenaria (quahog or cherry stone clam), Protothaca staminea (little neck clam), and the pteriomorphs, Hinnites multirugosus (rock scallop), Crassostrea virginica (eastern oyster), Mytilus edulis (eastern mussel), and Geukensia demissa (ribbed mussel). In addition, serotonin was assayed in the ventricles, auricles and heart-associated tissues in A. californica, M. mercenaria, H. multirugosus, and G. demissa with a sensitive radioenzymatic assay. Serotonin concentrations and the density of innervation were significantly higher in members of the subclass Heterodonta compared to the subclass Pteriomorpha. Serotonin immunoreactivity was observed in all species surveyed except G. demissa, which also contained relatively low concentrations of serotonin. Varicose fibers presumably corresponding to release sites were localized in the ventricles, auricles, and the auricular-ventricular valves. We hypothesize that in the species where serotonin-immunoreactive fibers are present, serotonin serves to modulate cardiac myogenic activity. The significance of the observed distribution and concentration of serotonin to the physiological effects of serotonin on cardiac function in these species is discussed. Springer-Verlag, 1992 Serotonin localization nationallicence Molluscan heart nationallicence Radioenzymatic assay nationallicence Cardiac innervation nationallicence Aplysia californica nationallicence Mercenaria mercenaria nationallicence Mytilus edulis nationallicence Crassostrea virginica nationallicence Geukensia demissa nationallicence Hinnites multitrugosus nationallicence Protothaca staminea (Mollusca) nationallicence Ono Joyce Department of Biological Science, California State University, 92634, Fullerton, CA, USA aut Hampton Jubal Department of Biological Science, California State University, 92634, Fullerton, CA, USA aut Koch Robert Department of Biological Science, California State University, 92634, Fullerton, CA, USA aut Cell and Tissue Research Springer-Verlag 269/3(1992-09-01), 421-430 0302-766X 269:3<421 1992 269 441 https://doi.org/10.1007/BF00353897 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00353897 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ono Joyce Department of Biological Science, California State University, 92634, Fullerton, CA, USA aut NATIONALLICENCE 700 1- Hampton Jubal Department of Biological Science, California State University, 92634, Fullerton, CA, USA aut NATIONALLICENCE 700 1- Koch Robert Department of Biological Science, California State University, 92634, Fullerton, CA, USA aut NATIONALLICENCE 773 0- Cell and Tissue Research Springer-Verlag 269/3(1992-09-01), 421-430 0302-766X 269:3<421 1992 269 441 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer