caa a22 4500 469083972 CHVBK 20180323132959.0 cr unu---uuuuu 170328e19920801xx s 000 0 eng 10.1007/BF00319610 doi (NATIONALLICENCE)springer-10.1007/BF00319610 Bromodeoxyuridine-immunohistochemistry on cellular differentiation and migration in the fundic gland of Xenopus laevis during development [Elektronische Daten] [Tsutomu Oinuma, Jun-ichi Kawano, Tatsuo Suganuma] Summary: Cellular differentiation and migration in the fundic glands of adult and larval Xenopus laevis have been examined using bromodeoxyuridine-immunohistochemistry. In the adult fundic gland, cumulative labeling with bromodeoxyuridine revealed a proliferative cell zone between the surface mucous cells and mucous neck cells, in what is referred to as the neck portion of the gland. The labeling-index of mucous neck cells had rapidly increased by week-5. The labeling-index of oxynticopeptic cells showed a more delayed increase until week-7, coincident with the decrease in the labeling of mucous neck cells. In the immature fundic glands of larvae, the labeled proliferating cells were randomly distributed throughout the developing gastric mucosa. During metamorphosis, the labeling-index of immature epithelial cells was highest at stage 63. Following administration of bromodeoxyurdine at this, stage, there was no significant loss of labeled epithelial cells during the metamorphosing period. Furthermore, there was no significant difference in the labeling-indices among the epithelial cells, such as surface mucous cells/generative cells, mucous neck cells, and oxynticopeptic cells, 7 days after administration. Cellular differentiation and migration pathways of epithelial cells in the fundic gland of adult X. laevis and its larvae are discussed. Springer-Verlag, 1992 Bromodeoxyuridine nationallicence Immunohistochemistry nationallicence Fundic gland nationallicence Stomach nationallicence Development nationallicence Xenopus laevis (Anura) nationallicence Oinuma Tsutomu Department of Anatomy, Miyazaki Medical College, 5200 Kihara, Kiyotake-cho, 889-16, Miyazaki, Japan aut Kawano Jun-ichi Department of Anatomy, Miyazaki Medical College, 5200 Kihara, Kiyotake-cho, 889-16, Miyazaki, Japan aut Suganuma Tatsuo Department of Anatomy, Miyazaki Medical College, 5200 Kihara, Kiyotake-cho, 889-16, Miyazaki, Japan aut Cell and Tissue Research Springer-Verlag 269/2(1992-08-01), 205-212 0302-766X 269:2<205 1992 269 441 https://doi.org/10.1007/BF00319610 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00319610 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Oinuma Tsutomu Department of Anatomy, Miyazaki Medical College, 5200 Kihara, Kiyotake-cho, 889-16, Miyazaki, Japan aut NATIONALLICENCE 700 1- Kawano Jun-ichi Department of Anatomy, Miyazaki Medical College, 5200 Kihara, Kiyotake-cho, 889-16, Miyazaki, Japan aut NATIONALLICENCE 700 1- Suganuma Tatsuo Department of Anatomy, Miyazaki Medical College, 5200 Kihara, Kiyotake-cho, 889-16, Miyazaki, Japan aut NATIONALLICENCE 773 0- Cell and Tissue Research Springer-Verlag 269/2(1992-08-01), 205-212 0302-766X 269:2<205 1992 269 441 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer