caa a22 4500 469090820 CHVBK 20180323133016.0 cr unu---uuuuu 170328e19920901xx s 000 0 eng 10.1007/BF00419664 doi (NATIONALLICENCE)springer-10.1007/BF00419664 Effect of delta-lysin on the phase transitions of lipid assemblies [Elektronische Daten] [V. Neitchev, K. Lohner, A. Collotto, P. Laggner] X-ray small-angle diffraction, differential scanning calorimetry (DSC), and temperature scanning densitometry (TSD) were used to study the effect of δ-lysin on the phase transitions of lipid assemblies from 1,2-0-dixehadecyl-sn-glycero-3-phosphoholine (DHPC). The experiments were carried out in excess of water in a temperature range of 0-55 °C, and at low peptide concentrations between 10-4 and 10-2 moles peptide per mole phospholipid. The incorporation of δ-lysin into lipid assemblies alters the lipid structure without significant changes on the temperatures of phase transition from gel to liquid crystalline phase. The temperature of the main transition was nearly unaffected. A reduction in the transition volume of the lipids with increasing concentrations of δ-lysin was observed. The minor changes in these parameters were interpreted as long-range structural changes caused by the peptide incorporation. The results are discussed in terms of the concept of cooperative phase transition of entire clusters occurring within a membrane implying that relative stable domains of gel phase, and liquid crystalline phase co-exist. Kluwer Academic Publishers, 1992 δ-lysin nationallicence lipid assemblies nationallicence cooperative transition nationallicence interdigitated structure nationallicence cluster nationallicence Neitchev V. Department of Biophysics, Bulgarian Academy of Sciences, 1113, Sofia, Bulgaria aut Lohner K. Institut für Biophysik und Röntgenstrukturforschung, Österreichische Akademie der Wissenschaften, Steyrergasse 17, A-8010, Graz, Austria aut Collotto A. Institut für Biophysik und Röntgenstrukturforschung, Österreichische Akademie der Wissenschaften, Steyrergasse 17, A-8010, Graz, Austria aut Laggner P. Institut für Biophysik und Röntgenstrukturforschung, Österreichische Akademie der Wissenschaften, Steyrergasse 17, A-8010, Graz, Austria aut Molecular Biology Reports Kluwer Academic Publishers 16/4(1992-09-01), 249-253 0301-4851 16:4<249 1992 16 11033 https://doi.org/10.1007/BF00419664 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00419664 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Neitchev V. Department of Biophysics, Bulgarian Academy of Sciences, 1113, Sofia, Bulgaria aut NATIONALLICENCE 700 1- Lohner K. Institut für Biophysik und Röntgenstrukturforschung, Österreichische Akademie der Wissenschaften, Steyrergasse 17, A-8010, Graz, Austria aut NATIONALLICENCE 700 1- Collotto A. Institut für Biophysik und Röntgenstrukturforschung, Österreichische Akademie der Wissenschaften, Steyrergasse 17, A-8010, Graz, Austria aut NATIONALLICENCE 700 1- Laggner P. Institut für Biophysik und Röntgenstrukturforschung, Österreichische Akademie der Wissenschaften, Steyrergasse 17, A-8010, Graz, Austria aut NATIONALLICENCE 773 0- Molecular Biology Reports Kluwer Academic Publishers 16/4(1992-09-01), 249-253 0301-4851 16:4<249 1992 16 11033 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer