caa a22 4500 469093382 CHVBK 20180323133024.0 cr unu---uuuuu 170328e19920801xx s 000 0 eng 10.1007/BF00584465 doi (NATIONALLICENCE)springer-10.1007/BF00584465 The pheromone signal pathway in Saccharomyces cerevisiae [Elektronische Daten] [James Konopka, Stanley Fields] Haploid cells of the yeastSaccharomyces cerevisiae normally undergo a budding life cycle, but after binding the appropriate mating pheromone they undergo a different developmental pathway that leads to conjugation. This intercellular communication between the two mating types activates a signal transduction pathway that stimulates the diverse physiological changes required for conjugation, such as induction of cell surface agglutinins, cell division arrest in G1, morphogenesis to form a conjugation tube, and cell fusion. The components of this pathway include a G protein-coupled receptor, several protein kinases, and a pheromone-responsive transcription factor. The molecular mechanisms that transduce the pheromone signal are remarkably similar to the mechanisms of hormone signaling used in multicellular organisms. Thus, the analysis of the pheromone signal pathway in yeast directly contributes to the study of cell growth and development in other eukaryotic organisms. Kluwer Academic Publishers, 1992 cell cycle control nationallicence G protein nationallicence hormone signaling nationallicence mating nationallicence transcription nationallicence yeast nationallicence Konopka James Department of Microbiology, State University of New York at Stony Brook, 11794-5222, Stony Brook, New York, USA aut Fields Stanley Department of Microbiology, State University of New York at Stony Brook, 11794-5222, Stony Brook, New York, USA aut Antonie van Leeuwenhoek Kluwer Academic Publishers 62/1-2(1992-08-01), 95-108 0003-6072 62:1-2<95 1992 62 10482 https://doi.org/10.1007/BF00584465 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00584465 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Konopka James Department of Microbiology, State University of New York at Stony Brook, 11794-5222, Stony Brook, New York, USA aut NATIONALLICENCE 700 1- Fields Stanley Department of Microbiology, State University of New York at Stony Brook, 11794-5222, Stony Brook, New York, USA aut NATIONALLICENCE 773 0- Antonie van Leeuwenhoek Kluwer Academic Publishers 62/1-2(1992-08-01), 95-108 0003-6072 62:1-2<95 1992 62 10482 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer