caa a22 4500 469093439 CHVBK 20180323133024.0 cr unu---uuuuu 170328e19920801xx s 000 0 eng 10.1007/BF00584461 doi (NATIONALLICENCE)springer-10.1007/BF00584461 The genetics of nuclear pre-mRNA splicing: a complex story [Elektronische Daten] [Jeremy Brown, Mary Plumpton, Jean Beggs] The occurrence of introns in nuclear precursor RNAs (pre-mRNAs) is widespread in eukaryotes, and the splicing process that removes them is basically the same in yeasts as it is in higher eukaryotes. Splicing takes place in a very large, multi-component complex, the spliceosome, and biochemical studies have been complicated by the large number of splicing factors involved. This review describes how genetic approaches used to study RNA splicing inSaccharomyces cerevisiae have complemented the biochemical studies and led to rapid advances in the field. Kluwer Academic Publishers, 1992 introns nationallicence pre-mRNA splicing nationallicence RNA processing nationallicence Saccharomyces cerevisiae nationallicence yeast genetics nationallicence Brown Jeremy Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings, Mayfield Road, EH9 3JR, Edinburgh, Scotland aut Plumpton Mary Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings, Mayfield Road, EH9 3JR, Edinburgh, Scotland aut Beggs Jean Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings, Mayfield Road, EH9 3JR, Edinburgh, Scotland aut Antonie van Leeuwenhoek Kluwer Academic Publishers 62/1-2(1992-08-01), 35-46 0003-6072 62:1-2<35 1992 62 10482 https://doi.org/10.1007/BF00584461 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00584461 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Brown Jeremy Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings, Mayfield Road, EH9 3JR, Edinburgh, Scotland aut NATIONALLICENCE 700 1- Plumpton Mary Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings, Mayfield Road, EH9 3JR, Edinburgh, Scotland aut NATIONALLICENCE 700 1- Beggs Jean Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings, Mayfield Road, EH9 3JR, Edinburgh, Scotland aut NATIONALLICENCE 773 0- Antonie van Leeuwenhoek Kluwer Academic Publishers 62/1-2(1992-08-01), 35-46 0003-6072 62:1-2<35 1992 62 10482 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer