caa a22 4500 469093773 CHVBK 20180323133025.0 cr unu---uuuuu 170328e19921201xx s 000 0 eng 10.1007/BF02576272 doi (NATIONALLICENCE)springer-10.1007/BF02576272 Experimental selective myocardial infarction in the dog without open-chest-surgery [Elektronische Daten] [Michael Beyer, Thomas Eggeling, Harald Hoffer, Stephan Mierdl, Ulrike Beyer, Andreas Hannekum] Summary: In 16 dogs, a selective myocardial infarction (MI) was experimentally provoked without open-chest-surgery by means of microspheres (MS) injected into a Judkins-catheter positioned into the left anterior descending coronary (LAD) under fluoroscopy. This was shown by ECG-abnormalities, increase of the serum-enzymes of myocardial necrosis, decrease of left ventricular end diastolic pressure (LVEDP), wedge pressure, and cardiac output. After 5 weeks, thoractomy showed a myocardial infarction limited to the anterior wall of the heart, which was of subendocardial location and consisted of multiple zones of microinfarction. Histological examination of the corresponding area showed necrosis of myocardial muscle fibres. Springer-Verlag, 1992 Experimental infarction nationallicence Catheterization nationallicence Beyer Michael Department of Chest and Cardiovascular Surgery, Ulm University Hospital, Steinhövelstrasse 9, W-7900, Ulm/Donau, Federal Republic of Germany aut Eggeling Thomas Department of Cardiology, Ulm University Hospital, Steinhövelstrasse 9, W-7900, Ulm/Donau, Federal Republic of Germany aut Hoffer Harald Department of Chest and Cardiovascular Surgery, Ulm University Hospital, Steinhövelstrasse 9, W-7900, Ulm/Donau, Federal Republic of Germany aut Mierdl Stephan Department of Chest and Cardiovascular Surgery, Ulm University Hospital, Steinhövelstrasse 9, W-7900, Ulm/Donau, Federal Republic of Germany aut Beyer Ulrike Department of Occupational Medicine, Ulm University Hospital, Steinhövelstrasse 9, W-7900, Ulm/Donau, Federal Republic of Germany aut Hannekum Andreas Department of Chest and Cardiovascular Surgery, Ulm University Hospital, Steinhövelstrasse 9, W-7900, Ulm/Donau, Federal Republic of Germany aut Research in Experimental Medicine Springer-Verlag 192/1(1992-12-01), 169-175 0300-9130 192:1<169 1992 192 433 https://doi.org/10.1007/BF02576272 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02576272 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Beyer Michael Department of Chest and Cardiovascular Surgery, Ulm University Hospital, Steinhövelstrasse 9, W-7900, Ulm/Donau, Federal Republic of Germany aut NATIONALLICENCE 700 1- Eggeling Thomas Department of Cardiology, Ulm University Hospital, Steinhövelstrasse 9, W-7900, Ulm/Donau, Federal Republic of Germany aut NATIONALLICENCE 700 1- Hoffer Harald Department of Chest and Cardiovascular Surgery, Ulm University Hospital, Steinhövelstrasse 9, W-7900, Ulm/Donau, Federal Republic of Germany aut NATIONALLICENCE 700 1- Mierdl Stephan Department of Chest and Cardiovascular Surgery, Ulm University Hospital, Steinhövelstrasse 9, W-7900, Ulm/Donau, Federal Republic of Germany aut NATIONALLICENCE 700 1- Beyer Ulrike Department of Occupational Medicine, Ulm University Hospital, Steinhövelstrasse 9, W-7900, Ulm/Donau, Federal Republic of Germany aut NATIONALLICENCE 700 1- Hannekum Andreas Department of Chest and Cardiovascular Surgery, Ulm University Hospital, Steinhövelstrasse 9, W-7900, Ulm/Donau, Federal Republic of Germany aut NATIONALLICENCE 773 0- Research in Experimental Medicine Springer-Verlag 192/1(1992-12-01), 169-175 0300-9130 192:1<169 1992 192 433 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer