caa a22 4500 469093781 CHVBK 20180323133025.0 cr unu---uuuuu 170328e19921201xx s 000 0 eng 10.1007/BF02576273 doi (NATIONALLICENCE)springer-10.1007/BF02576273 Histopathology of experimental spinal cord trauma [Elektronische Daten] Comparison of treatment with TRH, naloxone, and dexamethasone [H. Akdemir, A. Pasaoĝlu, F. Öztürk, A. Selçuklu, K. Koç, A. Kurtsoy] Summary: The results of treatment with thyrotropin-releasing hormone (TRH), naloxone and dexamethasone treatments albino rats with experimental spinal cord injury were compared. All the animals were made paraplegic by the application clip method of Rivlin and Tator. Treatment was administered i.p. as bolus injections in two doses, at 45 and 120 min after the injury. Animals were allocated randomly to four experimental groups: (1) TRH (0.6 mg per dose), (2) naloxone (0.8 mg per dose), (3) dexamethasone (0.6 mg per dose), and (4) control (saline). TRH-treated rats showed significantly better histopathological scores than either naloxone or dexamethasone-treated ones (Kruskal Wallis: 24.058P<0.001). Springer-Verlag, 1992 Spinal cord injury nationallicence TRH nationallicence Naloxone nationallicence Dexamethasone nationallicence Akdemir H. Department of Neurosurgery, Erciyes University Medical School, TR-38039, Kayseri, Turkey aut Pasaoĝlu A. Department of Neurosurgery, Erciyes University Medical School, TR-38039, Kayseri, Turkey aut Öztürk F. Department of Pathology, Erciyes University Medical School, TR-38039, Kayseri, Turkey aut Selçuklu A. Department of Neurosurgery, Erciyes University Medical School, TR-38039, Kayseri, Turkey aut Koç K. Department of Neurosurgery, Erciyes University Medical School, TR-38039, Kayseri, Turkey aut Kurtsoy A. Department of Neurosurgery, Erciyes University Medical School, TR-38039, Kayseri, Turkey aut Research in Experimental Medicine Springer-Verlag 192/1(1992-12-01), 177-183 0300-9130 192:1<177 1992 192 433 https://doi.org/10.1007/BF02576273 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02576273 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Akdemir H. Department of Neurosurgery, Erciyes University Medical School, TR-38039, Kayseri, Turkey aut NATIONALLICENCE 700 1- Pasaoĝlu A. Department of Neurosurgery, Erciyes University Medical School, TR-38039, Kayseri, Turkey aut NATIONALLICENCE 700 1- Öztürk F. Department of Pathology, Erciyes University Medical School, TR-38039, Kayseri, Turkey aut NATIONALLICENCE 700 1- Selçuklu A. Department of Neurosurgery, Erciyes University Medical School, TR-38039, Kayseri, Turkey aut NATIONALLICENCE 700 1- Koç K. Department of Neurosurgery, Erciyes University Medical School, TR-38039, Kayseri, Turkey aut NATIONALLICENCE 700 1- Kurtsoy A. Department of Neurosurgery, Erciyes University Medical School, TR-38039, Kayseri, Turkey aut NATIONALLICENCE 773 0- Research in Experimental Medicine Springer-Verlag 192/1(1992-12-01), 177-183 0300-9130 192:1<177 1992 192 433 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer