caa a22 4500 469094052 CHVBK 20180323133026.0 cr unu---uuuuu 170328e19921201xx s 000 0 eng 10.1007/BF02576293 doi (NATIONALLICENCE)springer-10.1007/BF02576293 Gastric mucosal blood flow distribution in the CCl4-induced cirrhotic rat—a model of portal hypertensive gastropathy? [Elektronische Daten] [K. Kotzampassi, E. Eleftheriadis] Summary: Because the carbon tetrachloride-induced cirrhotic rat model is considered to be the closest to the clinical situation of the cirrhotic patient, the discovery of congestive gastropathy in such rats would enable the development of a useful research model. By the use of laser-Doppler technology, gastric mucosal blood flow was assessed on 14 defined points of the stomach in 16 cirrhotic and 16 matched healthy rats, in an effort at in vivo mapping of the gastric mucosal microcirculation. Our findings of mucosal congestion in the cirrhotic stomach (reduced mucosal blood flow in the gastric corpus) are well matched with the distribution of gastric mucosal blood flow in the cirrhotic patient. These findings suggest that a rat's gastric mucosa could be used for studies of portal hypertensive gastropathy. Springer-Verlag, 1992 Experimental cirrhosis nationallicence Gastric mucosal blood flow nationallicence Laser-Doppler flowmetry nationallicence Kotzampassi K. Department of Surgery, University of Thessaloniki, GR-54006, Thessaloniki, Greece aut Eleftheriadis E. Department of Surgery, University of Thessaloniki, GR-54006, Thessaloniki, Greece aut Research in Experimental Medicine Springer-Verlag 192/1(1992-12-01), 367-372 0300-9130 192:1<367 1992 192 433 https://doi.org/10.1007/BF02576293 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02576293 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kotzampassi K. Department of Surgery, University of Thessaloniki, GR-54006, Thessaloniki, Greece aut NATIONALLICENCE 700 1- Eleftheriadis E. Department of Surgery, University of Thessaloniki, GR-54006, Thessaloniki, Greece aut NATIONALLICENCE 773 0- Research in Experimental Medicine Springer-Verlag 192/1(1992-12-01), 367-372 0300-9130 192:1<367 1992 192 433 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer