caa a22 4500 469094079 CHVBK 20180323133026.0 cr unu---uuuuu 170328e19921201xx s 000 0 eng 10.1007/BF02576254 doi (NATIONALLICENCE)springer-10.1007/BF02576254 Treatment of acute spinal cord injuries: comparison of thyrotropin-releasing hormone and nimodipine [Elektronische Daten] [S. Ceylan, K. Ilbay, S. Baykal, S. Ceylan, U. Şener, M. Özmenoĝlu, M. Kalelioĝlu, F. Aktürk, S. Komsuoĝlu, A. Özoran] Summary: The effects of nimodipine and thyrotropin-releasing hormone (TRH) were compared in a clip-compression model of experimental spinal cord injuries (SCI) in rats. Thirty rats received a 50-g clip-compression injury on the cord at T9. Ten rats were given 0.02 mg/kg nimodipine and dextran 40 (3ml) i.v. 1h after injury. Ten rats were given 2 mg/kg TRH and dextran 40 (3ml) i.v. 1h after injury followed by 1 mg/kg per hour for 4h. The remaining ten rats were given only saline. TRH treatment significantly improved somatosensory-evoked potentials (SEPs) and mean arterial blood pressures (MABPs), whereas nimodipine treatment had no effect on these variables (Fisher's exact test (P<0.01). Springer-Verlag, 1992 Spinal cord injury nationallicence TRH nationallicence Nimodipine nationallicence Clip compression nationallicence Ceylan S. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut Ilbay K. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut Baykal S. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut Şener U. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut Özmenoĝlu M. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut Kalelioĝlu M. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut Aktürk F. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut Komsuoĝlu S. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut Özoran A. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut Research in Experimental Medicine Springer-Verlag 192/1(1992-12-01), 23-33 0300-9130 192:1<23 1992 192 433 https://doi.org/10.1007/BF02576254 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02576254 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ceylan S. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut NATIONALLICENCE 700 1- Ilbay K. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut NATIONALLICENCE 700 1- Baykal S. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut NATIONALLICENCE 700 1- Şener U. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut NATIONALLICENCE 700 1- Özmenoĝlu M. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut NATIONALLICENCE 700 1- Kalelioĝlu M. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut NATIONALLICENCE 700 1- Aktürk F. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut NATIONALLICENCE 700 1- Komsuoĝlu S. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut NATIONALLICENCE 700 1- Özoran A. Departments of Neurosurgery, Neurology and Histology, KTÜ Medical Faculty, TR-61080, Trabzon, Turkey aut NATIONALLICENCE 773 0- Research in Experimental Medicine Springer-Verlag 192/1(1992-12-01), 23-33 0300-9130 192:1<23 1992 192 433 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer