caa a22 4500 469094699 CHVBK 20180323133027.0 cr unu---uuuuu 170328e19921001xx s 000 0 eng 10.1007/BF00190984 doi (NATIONALLICENCE)springer-10.1007/BF00190984 MR imaging of skeletal metastases from medulloblastoma [Elektronische Daten] [Paul Algra, Tjeerd Postma, Cornelis Van Groeningen, Paul Van Der Valk, Johan Bloem, Jaap Valk] The findings of MR imaging in 3 patients with bone metastases from medulloblastoma are reported. The first patient showed focal lesions of low signal intensity on T1-weighted spin echo images at a time when bone scintigraphy was negative for metastases. This patient later developed extensive osteosclerotic lesions visible on plain films. The bone marrow of the second patient showed diffuse low signal intensity on T1-weighted images. After chemotherapy the signal intensity of the bone marrow increased which correlated with a return of normal hematopoietic tissue. A response to chemotherapy was also found on MR imaging and repeat bone marrow biopsies in a third patient. A consistent finding was a low signal intensity on pre-gadolinium images, but the pattern (focal or diffuse abnormal signal intensity) was different in each patient. To our knowledge, this is the first report on MR imaging findings in bone metastases from medulloblastoma. International Skeletal Society, 1992 Medulloblastoma nationallicence Extraneural spread nationallicence Bone metastases nationallicence MR imaging nationallicence Algra Paul Department of Diagnostic Radiology, Free University Hospital, Amsterdam, The Netherlands aut Postma Tjeerd Department of Neurology, Free University Hospital, Amsterdam, The Netherlands aut Van Groeningen Cornelis Department of Medical Oncology, Free University Hospital, Amsterdam, The Netherlands aut Van Der Valk Paul Department of Pathology, Free University Hospital, Amsterdam, The Netherlands aut Bloem Johan Department of Diagnostic Radiology, University Hospital Leiden, The Netherlands aut Valk Jaap Department of Diagnostic Radiology, Free University Hospital, Amsterdam, The Netherlands aut Skeletal Radiology Springer-Verlag 21/7(1992-10-01), 425-430 0364-2348 21:7<425 1992 21 256 https://doi.org/10.1007/BF00190984 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00190984 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Algra Paul Department of Diagnostic Radiology, Free University Hospital, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Postma Tjeerd Department of Neurology, Free University Hospital, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Van Groeningen Cornelis Department of Medical Oncology, Free University Hospital, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Van Der Valk Paul Department of Pathology, Free University Hospital, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Bloem Johan Department of Diagnostic Radiology, University Hospital Leiden, The Netherlands aut NATIONALLICENCE 700 1- Valk Jaap Department of Diagnostic Radiology, Free University Hospital, Amsterdam, The Netherlands aut NATIONALLICENCE 773 0- Skeletal Radiology Springer-Verlag 21/7(1992-10-01), 425-430 0364-2348 21:7<425 1992 21 256 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer