caa a22 4500 469095059 CHVBK 20180323133028.0 cr unu---uuuuu 170328e19920501xx s 000 0 eng 10.1007/BF00243065 doi (NATIONALLICENCE)springer-10.1007/BF00243065 Quantitative early phase scintigraphy in the prediction of healing of tibial fractures [Elektronische Daten] [A. Wallace, R. Strachan, A. Blane, J. Best, S. Hughes] Imaging with technetium-99m methylene diphosphonate (99mTc-MDP) is established in the diagnosis of infection, neoplasia and ischaemic necrosis in orthopaedic practice, but its role in fracture healing is less well-defined. Previous studies have shown a relationship between fracture site activity (region A), activity in adjacent normal bone (region C) and time to union. The predictive value of the A/C ratio of the image obtained 300-800 s after injection was assessed in a prospective study of 50 patients with closed tibial fractures managed with plaster casts, external fixators and intramedullary nails. There were significant differences in absolute uptake and A/C ratio between the three groups (P<0.05), but this was not related to time to union. Reamed nailing alters the distribution of 99m-Tc-MDP uptake so as to reduce the A/C ratio (1.10+0.20), but there is a promising role for early phase bone scanning in non-operative (A/C=1.40+0.21) or externally fixed (A/C=1.26+0.22) fractures in conjunction with other non-invasive methods of monitoring the biomechanical environment. International Skeletal Society, 1992 Tibial fracture nationallicence Technetium-99m methylene diphosphonate nationallicence Bone blood flow nationallicence Intramedullary nail nationallicence External fixation nationallicence Wallace A. Department of Orthopaedic Surgery, University of Edinburgh Medical School, Edinburgh aut Strachan R. Department of Orthopaedic Surgery, University of Edinburgh Medical School, Edinburgh aut Blane A. Department of Medical Radiology, University of Edinburgh, Royal Infirmary, Edinburgh aut Best J. Department of Medical Radiology, University of Edinburgh, Royal Infirmary, Edinburgh aut Hughes S. Department of Orthopaedic Surgery, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK aut Skeletal Radiology Springer-Verlag 21/4(1992-05-01), 241-245 0364-2348 21:4<241 1992 21 256 https://doi.org/10.1007/BF00243065 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00243065 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wallace A. Department of Orthopaedic Surgery, University of Edinburgh Medical School, Edinburgh aut NATIONALLICENCE 700 1- Strachan R. Department of Orthopaedic Surgery, University of Edinburgh Medical School, Edinburgh aut NATIONALLICENCE 700 1- Blane A. Department of Medical Radiology, University of Edinburgh, Royal Infirmary, Edinburgh aut NATIONALLICENCE 700 1- Best J. Department of Medical Radiology, University of Edinburgh, Royal Infirmary, Edinburgh aut NATIONALLICENCE 700 1- Hughes S. Department of Orthopaedic Surgery, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK aut NATIONALLICENCE 773 0- Skeletal Radiology Springer-Verlag 21/4(1992-05-01), 241-245 0364-2348 21:4<241 1992 21 256 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer