caa a22 4500 469102055 CHVBK 20180323133047.0 cr unu---uuuuu 170328e19920601xx s 000 0 eng 10.1007/BF00129082 doi (NATIONALLICENCE)springer-10.1007/BF00129082 The cellulose paradox: pollutant par excellence and/or a reclaimable natural resource? [Elektronische Daten] [Edward Bayer, Raphael Lamed] The various aspects of cellulose as a pollutant are considered in view of its lack of toxicity on the one hand and its recalcitrant durable nature on the other. The microbial degradation of cellulosics is discussed, and the contrast between its success in handling natural cellulosic wastes versus its failure to cope with man-made refuse is described. Research carried out in the past decade has demonstrated that cellulolytic organisms are provided with cell surface multifunctional multienzyme conglomerates, called cellulosomes, which are capable of solubilizing solid cellulosic substrates. The intriguing properties of such complexes include their cohesive nature, their many enzymatic components, and a characteristic glycosylated cellulose-binding, ‘scaffolding' component. The latter appears to serve as a substrate-targeting carrier, which delivers the other (hydrolytic) components to the cellulose. Progress in establishing efficient model systems for in vitro solubilization of purified cellulose or natural cellulosic substrates has been achieved using purified cellulosome preparations, fortified with β-glucosidase and pectinase. The latter enzymes were required in order to alleviate the phenomenon of product inhibition which reduces the efficiency of the free cellulosome. Such combined enzyme systems are proposed as examples of future tailor-made cellulolytic systems for the degradation of natural cellulosics. Kluwer Academic Publishers, 1992 cellulose (solubilization of) nationallicence pollution nationallicence cellulosome nationallicence Clostridium thermocellum nationallicence multienzyme systems nationallicence Bayer Edward Department of Biophysics, The Weizmann Institute of Science, Rehovot, Israel aut Lamed Raphael Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv, Israel aut Biodegradation Kluwer Academic Publishers 3/2-3(1992-06-01), 171-188 0923-9820 3:2-3<171 1992 3 10532 https://doi.org/10.1007/BF00129082 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00129082 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bayer Edward Department of Biophysics, The Weizmann Institute of Science, Rehovot, Israel aut NATIONALLICENCE 700 1- Lamed Raphael Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv, Israel aut NATIONALLICENCE 773 0- Biodegradation Kluwer Academic Publishers 3/2-3(1992-06-01), 171-188 0923-9820 3:2-3<171 1992 3 10532 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer