caa a22 4500 469114274 CHVBK 20180323133120.0 cr unu---uuuuu 170328e19921101xx s 000 0 eng 10.1007/BF00420063 doi (NATIONALLICENCE)springer-10.1007/BF00420063 Immunoreactive neuropeptide nerves in ligamentous tissue in chronic shoulder pain [Elektronische Daten] [Y. Konttinen, S. Santavirta, P. Paavolainen, I. Antti-Poika, T. Tiainen, D. Nordström, M. Hukkanen] Summary: Coracoacromial ligament and periligamentous fatty and loose connective tissue obtained during Neer's acromioplasty in patients with chronic painful rotator cuff tendinitis/impingement syndrome was studied for possible signs of inflammatory involvement and for the presence of neuropeptide-containing nerves, using routine histology and immunoperoxidase staining. No accumulations of inflammatory cells were found in the tissues studied. The dense ligamentous tissue proper was practically aneural, as was seen in staining for the generalized neuronal markers protein gene product 9.5 and synaptophysin. In contrast, the periligamentous fatty and loose connective tissue was innervated. Almost all nerves in such tissue contained C-flanking peptide of neuropeptide Y, whereas substance P, calcitonin gene-related peptide, and vasoactive intestinal peptide-containing nerves were not found at all or were extremely rare. This suggests that the coracoacromial ligament is not a target of irritative inflammation. In the periligamentary sheath, nerves containing markers for the C-type nociceptive pain fibers were practically absent and all local nerves were postganglionic sympathetic vasoregulatory nerves. Springer-Verlag, 1992 Konttinen Y. Department of Anatomy, University of Helsinki, Finland aut Santavirta S. Orthopaedic Hospital of the Invalid Foundation, Helsinki, Finland aut Paavolainen P. Orthopaedic Hospital of the Invalid Foundation, Helsinki, Finland aut Antti-Poika I. Peijas-Rekola Hospital, Vantaa, Finland aut Tiainen T. Peijas-Rekola Hospital, Vantaa, Finland aut Nordström D. Fourth Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland aut Hukkanen M. Department of Histochemistry, Royal Postgraduate Medical School, London, UK aut Archives of Orthopaedic and Trauma Surgery Springer-Verlag 111/6(1992-11-01), 341-344 0936-8051 111:6<341 1992 111 402 https://doi.org/10.1007/BF00420063 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00420063 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Konttinen Y. Department of Anatomy, University of Helsinki, Finland aut NATIONALLICENCE 700 1- Santavirta S. Orthopaedic Hospital of the Invalid Foundation, Helsinki, Finland aut NATIONALLICENCE 700 1- Paavolainen P. Orthopaedic Hospital of the Invalid Foundation, Helsinki, Finland aut NATIONALLICENCE 700 1- Antti-Poika I. Peijas-Rekola Hospital, Vantaa, Finland aut NATIONALLICENCE 700 1- Tiainen T. Peijas-Rekola Hospital, Vantaa, Finland aut NATIONALLICENCE 700 1- Nordström D. Fourth Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland aut NATIONALLICENCE 700 1- Hukkanen M. Department of Histochemistry, Royal Postgraduate Medical School, London, UK aut NATIONALLICENCE 773 0- Archives of Orthopaedic and Trauma Surgery Springer-Verlag 111/6(1992-11-01), 341-344 0936-8051 111:6<341 1992 111 402 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer