caa a22 4500 469114304 CHVBK 20180323133120.0 cr unu---uuuuu 170328e19921101xx s 000 0 eng 10.1007/BF00420062 doi (NATIONALLICENCE)springer-10.1007/BF00420062 Inflammation of the subacromial bursa in chronic shoulder pain [Elektronische Daten] [S. Santavirta, Y. Konttinen, I. Antti-Poika, D. Nordström] Summary: Subacromial bursal tissue was studied in 12 patients operated on for painful (10 patients with constant pain and 2 patients with pain on motion) rotator cuff tendinitis/impingement syndrome. The Neer acromioplasty technique was used. Six patients had moderate inflammatory changes and one had a slight inflammation. In three of the five remaining patients, the subacromial bursa did not show any signs of inflammatory involvement, but patients experienced pain at rest and at night, reflecting clinical inflammation in tissues other than the bursa. The two patients with pain only on strain did not show inflammation of the bursa. Immunohistochemical typing of the bursal tissue disclosed a typical chronic mononuclear cell infiltrate consisting mainly of CD2-positive T lymphocytes (50-80% of all inflammatory cells), accompanied by less frequent CD11b (C3bi receptor) -positive monocyte/macrophages (10-40%). The relative paucity of plasmablasts/plasma cells expressing PCA-1 suggests this to be an inflammatory rather than an immune response. Active involvement of some of the local cells is suggested to be the source of algogenic and hyperalgesic substances contributing to pain in chronic shoulder pain syndromes. Springer-Verlag, 1992 Santavirta S. Orthopaedic Hospital of the Invalid Foundation, Tenholantie 10, SF-00280, Helsinki 28, Finland aut Konttinen Y. Institute of Molecular Immunology, Hospital for Joint Diseases, Orthopedic Institute, New York, NY, USA aut Antti-Poika I. Peijas-Rekola Hospital, Vantaa, Finland aut Nordström D. Fourth Department of Medicine, Helsinki University Central Hospital, SF-00170, Helsinki 17, Finland aut Archives of Orthopaedic and Trauma Surgery Springer-Verlag 111/6(1992-11-01), 336-340 0936-8051 111:6<336 1992 111 402 https://doi.org/10.1007/BF00420062 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00420062 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Santavirta S. Orthopaedic Hospital of the Invalid Foundation, Tenholantie 10, SF-00280, Helsinki 28, Finland aut NATIONALLICENCE 700 1- Konttinen Y. Institute of Molecular Immunology, Hospital for Joint Diseases, Orthopedic Institute, New York, NY, USA aut NATIONALLICENCE 700 1- Antti-Poika I. Peijas-Rekola Hospital, Vantaa, Finland aut NATIONALLICENCE 700 1- Nordström D. Fourth Department of Medicine, Helsinki University Central Hospital, SF-00170, Helsinki 17, Finland aut NATIONALLICENCE 773 0- Archives of Orthopaedic and Trauma Surgery Springer-Verlag 111/6(1992-11-01), 336-340 0936-8051 111:6<336 1992 111 402 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer