caa a22 4500 469115211 CHVBK 20180323133122.0 cr unu---uuuuu 170328e19920801xx s 000 0 eng 10.1007/BF00731166 doi (NATIONALLICENCE)springer-10.1007/BF00731166 Specificity of Amaranthus leucocarpus lectin [Elektronische Daten] [Edgar Zenteno, Ricardo Lascurain, Luis Montaño, Lorena Vazquez, Henri Debray, Jean Montreuil] We have demonstrated thatAmaranthus leucocarpus lectin hemagglutinating activity was powerfully inhibited by the T-antigen, containing Gal(β1-3)GalNAc(α1-3)Ser/Thr, and the Tn-antigen, which contains GalNAc(α1-3)Ser/Thr. This suggests that the acetamido group at C-2 and the axial -OH at C-4 of theN-acetyl-D-galactopyranosylamine ring are important for lectin binding. The hemagglutination assays also established that desialylated and Pronase-treated human typeO erythrocytes with an M phenotype were better recognized than erythrocytes from all other blood groups. The recognition was dependent on pH and ionic strength. Chapman & Hall, 1992 plant lectin nationallicence Amaranthus leucocarpus nationallicence T and Tn antigen-specific lectin nationallicence Zenteno Edgar Departamento Biologia Experimental, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos, Mexico aut Lascurain Ricardo Departamento Bioquímica, Facultad de Medicina, UNAM, 04510 D.F., Mexico aut Montaño Luis Departamento Biología, Instituto Nacional de Cardiología, 14000 D.F., Mexico aut Vazquez Lorena Departamento Biologia Experimental, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos, Mexico aut Debray Henri Laboratoire de Chimie Biologique (Unité mixte du CNRS No 111), Université des Sciences et Techniques de Lille Flandres-Artois, 59655, Villeneuve d'Ascq Cedex, France aut Montreuil Jean Laboratoire de Chimie Biologique (Unité mixte du CNRS No 111), Université des Sciences et Techniques de Lille Flandres-Artois, 59655, Villeneuve d'Ascq Cedex, France aut Glycoconjugate Journal Kluwer Academic Publishers 9/4(1992-08-01), 204-208 0282-0080 9:4<204 1992 9 10719 https://doi.org/10.1007/BF00731166 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00731166 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Zenteno Edgar Departamento Biologia Experimental, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos, Mexico aut NATIONALLICENCE 700 1- Lascurain Ricardo Departamento Bioquímica, Facultad de Medicina, UNAM, 04510 D.F., Mexico aut NATIONALLICENCE 700 1- Montaño Luis Departamento Biología, Instituto Nacional de Cardiología, 14000 D.F., Mexico aut NATIONALLICENCE 700 1- Vazquez Lorena Departamento Biologia Experimental, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos, Mexico aut NATIONALLICENCE 700 1- Debray Henri Laboratoire de Chimie Biologique (Unité mixte du CNRS No 111), Université des Sciences et Techniques de Lille Flandres-Artois, 59655, Villeneuve d'Ascq Cedex, France aut NATIONALLICENCE 700 1- Montreuil Jean Laboratoire de Chimie Biologique (Unité mixte du CNRS No 111), Université des Sciences et Techniques de Lille Flandres-Artois, 59655, Villeneuve d'Ascq Cedex, France aut NATIONALLICENCE 773 0- Glycoconjugate Journal Kluwer Academic Publishers 9/4(1992-08-01), 204-208 0282-0080 9:4<204 1992 9 10719 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer